Interactive Transcript
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Here is an example of an IDH mutated glioma
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in a patient, 28-year-old male,
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presenting with headaches and otherwise clinically intact.
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You can see that MRI shows a very large
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tumor involving the frontal lobe.
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It's actually extending across the midline by the volatile
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frontal lobe involvement,
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with hardly any edema
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around this very well-defined mass,
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which shows some heterogenous fatty enhancement
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within the tumor, and more importantly,
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if you look at the CT scan done a day earlier,
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it actually shows you that this tumor
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has some areas of calcification,
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which in fact could also be confirmed on
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the susceptibility weighted imaging.
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All our brain tumor patients
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also undergo susceptibility weighted imaging sequences,
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and you can see these tumors
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are mutated gliomas.
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They might show areas of hemorrhage
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as this one is showing,
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but also some of these susceptibility blooming signal,
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which we are seeing,
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is also related to calcification.
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As you can see, some of these areas are dark on
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phase imaging right over here,
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which kind of corresponds to the calcification
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we saw on the CT scan.
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So, you know, these tumors,
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they could be calcified,
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and once we see the calcification in a tumor,
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which looks like that, in the frontal lobe in a young patient,
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you can suggest a diagnosis of an oligodendroglioma,
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which this turned out.
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