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Here is another example.

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A 28-year-old male patient presenting with headaches,

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had this large tumor, very well-defined, homogeneously

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bright on T2-weighted images in the right frontal lobe,

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shows dark signal on the FLAIR images.

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Majority of the tumor,

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the central part of the tumor, showing you dark signal,

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loss of signal on the FLAIR images,

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except this peripheral thin rim of bright signal

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and again, not showing contrast enhancement,

0:32

as you can see on the post-contrast images.

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And showing you a rather facilitated diffusion on

0:38

the diffusion-weighted images. And again,

0:41

this is another example of a classic T2

0:44

FLAIR mismatch sign,

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as we now know is...

0:48

and proven to be an IDH-mutated,

0:51

non-correlated 1P/19Q co-relation was found,

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and an IDH-mutated astrocytoma.