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Wk 3, Case 2 - Review

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Another case of treated breast

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cancer status post mastectomy.

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So, the history that was provided here was

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that this is a high-risk screening breast MR.

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She's a younger woman, 58, and,

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good on each one of you if you don't

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think 58 is young. I'm at

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the stage, I think 58 is pretty young.

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Pretty young.

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Um, she has a prior history of right

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breast cancer status post right

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mastectomy and tram reconstruction.

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So I'm going to convince you that once you've

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seen a TRAM and once you recognize a TRAM,

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you're never not going to recognize it.

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They all look exactly alike.

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Like, or they look pretty,

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they look pretty darn alike.

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So, um, so let me just scroll here.

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We're going to start at the top.

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See, I'm even struggling with

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somebody else's platform here.

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Okay, we're going to start at the top and

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come down, and it's evident immediately

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that we don't have symmetric breasts.

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Parenchyma, um, that we have the contralateral

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left breast looks far more normal on the

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T1 pre non-fat sets, with returns

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in terms of rests of parenchyma,

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glops of tissue as you, as it were.

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And then, um, also very

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similar, different surgery.

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I'm sorry, different surgeon,

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but analogous appearance.

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We've got the abdominal fat.

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And then we've got that little bit of

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leftover epithelium that used to be the

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chest, and then we've got that line, and

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then we, we have the, we have the, um,

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the vascularized flap itself, um, here.

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Now, what's going to be different in this

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case is this case has a lot more going on

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than did the, than did my asymptomatic

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completely normal TRAM case from a moment ago.

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And in fact, this was what, what, in part,

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was plaguing the patient. The patient

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had pain; the patient had palpable masses,

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and then the question becomes, well, what

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are these? Are these of concern at all?

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So I'm going to remind you in terms

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of our, I'm going to remind you.

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So I want you to just be reminded of this.

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Be reminded of this, um, content of fat here.

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Um, and there's, it's a very typical

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appearance, um, uh, um, for fat.

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You can actually see the fat,

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the fat, uh, the fat intensity.

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All right, and then, um, this

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is a very straightforward answer

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once I get it re-rotated here.

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Rotate, rotate, and re-windowed.

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And you'll see that, um, there we go.

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What we have is, um, there we go.

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So we have, um, tissue, uh, that

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is actually overtly fat-containing.

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Admittedly, some of it enhances in

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an inflammatory manner, admittedly.

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But nonetheless, the tissue itself

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is, um, consistent with fat necrosis.

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So we have a TRAM with fat necrosis.

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Arguably, MR is not the manner to

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actually, um, to actually determine

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that we are just having to avoid, um,

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the teaching point of this case.

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Honestly, it's avoiding an overdiagnosis

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of fat necrosis as malignancy.

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So in this case, the next step would

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be a diagnostic mammogram, um, plus

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minus ultrasound because the findings

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will be very characteristic, as we

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all know, as breast on, um, mammogram.

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Okay, any specific questions? Classically, you

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would just use split screens or in our case,

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you know, 2 on 1, or a 4 on 1, and just confirm

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that the enhancing masses.

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Are indeed, you flip these enhancing masses.

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I can get this window and leveled

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so we can even see where we are.

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There we go.

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That the, um, that the, that the

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enhancing masses are, in fact, merely fat.

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So another, uh, utility of those, um, uh, of

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starting with the pre, um, the pre-contrast

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non-fat set images. In this case, it very

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nicely delineates both the anatomy, the fact

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that she's a high-risk patient who has had

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breast cancer, but also all of the, um, fat.

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Fat necrosis is quite common, by the

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way, in the setting of the flaps.

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They've gotten better at it, uh,

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but, uh, fat necrosis now plagues us

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in the setting of the oncoplasties.

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Do, do any of you have sites that

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have oncoplastic surgeons that

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are doing a lot of fat grafting?

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In which case, you should be

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giving this, uh, along with me.

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We could do this session in tandem.

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We could do a whole session on fat necrosis

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together because we, many of us in the

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business learned about fat necrosis in

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the setting of, in the setting of the

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patients who had had these trans flaps.

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They're the ones that seem

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to be the most plagued by it.

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Although certainly, lots of

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lumpectomy patients have

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fat necrosis, but now, no doubt,

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hands down, we see it most frequently

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in the patients who have had oncoplasty

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procedures, in whom the, in whom the, the,

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the fat, the free fat, the free fat in.

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Actions and, um, uh, other, um, other plastic

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procedures are yielding a lot of fat necrosis.

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So anyway, anybody have any experience

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with that at your institution?

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If not, it's to come, I promise that made it to

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you yet breast breast surgery, a lot of plastic

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surgeons at this point for patient satisfaction.

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So patient satisfaction is superior.

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All right, so those were the

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teaching points on that case.

Report

HISTORY: 58 year old woman, high risk screening breast MRI, prior history of right breast invasive ductal cancer s/p right mastectomy and TRAM flap reconstruction 1 year prior to this MRI.

Summary of prior imaging:

Mammography: No right breast imaging after surgery. Left breast BI-RAD 1
Ultrasound: NA
Breast MRI: NA

FINDINGS

Quality control issues: ☒None ☐Poor/lack contrast bolus ☐Poor fat suppression
☐Susceptibility ☐Movement ☐Other

Background Parenchymal Enhancement: Moderate

Amount of Fibroglandular Tissue: Heterogenous glandular tissue

LEFT BREAST

Narrative: Scattered foci of enhancement consistent with fibrocystic/hormonal changes

Associated findings LEFT breast: ☐Nipple retraction, ☐Nipple involvement, ☐Skin
retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory,
☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings LEFT breast: ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening, ☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

BI-RADS:2: Benign

Fat containing lesions LEFT: ☐Fat necrosis, ☐Hamartoma, ☐Post-operative
seroma/hematoma with fat

Lymph nodes LEFT: ☒Normal axillary, ☐Abnormal axillary, ☐ Abnormal internal mammary

RIGHT BREAST

Narrative: Post TRAM flap findings with skin thickening. Multiple areas of non-mass enhancement surrounding areas of fat consistent with fat necrosis.

Associated findings RIGHT breast: ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory,☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings RIGHT breast: ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☒Post therapy skin/trabecular thickening, ☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions RIGHT: ☒Fat necrosis, ☐Hamartoma, ☐Post-operative
seroma/hematoma with fat

Lymph nodes RIGHT: ☒Normal axillary, ☐Abnormal axillary, ☐ Abnormal internal mammary

BI-RADS:2: Benign

Extramammary findings: None

SUMMARY: Extensive fat necrosis right breast following TRAM flap reconstruction. No evidence malignancy.

RECOMMENDATIONS: Continue annual high risk screening

Case Discussion

Faculty

Petra J Lewis, MBBS

Professor of Radiology and OBGYN

Dartmouth-Hitchcock Medical Center & Geisel School of Medicine at Dartmouth

Sheryl G. Jordan, MD

Professor, Department of Radiology

University of North Carolina School of Medicine

Ryan W. Woods, MD, MPH

Assistant Professor of Radiology

University of Wisconsin School of Medicine and Public Health

Tags

Women's Health

MRI

Breast

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