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Wk 3, Case 3 - Review

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0:00

This is left breast IDC.

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Prior lumpectomy patient.

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Okay.

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And I'm going to start at the top and then

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come down, and you can see that these things

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are pretty readily seen, pretty

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evident, uh, up front

0:17

on these T1 pre, uh, non-fat sets.

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'Cause you can actually see the axilla, um,

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the axillary surgical site compared to the

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normal right side, and then coming down.

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And then you can begin to see some

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other subtle but possible, uh,

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sites of architectural distortion.

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She's also got susceptibility

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artifact from clips.

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Um, so that's our, that's

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our lay of the land anatomy.

0:43

All right.

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So these are the subtracted images we, as we

0:46

talked about, and I have reformatted them.

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And so, um, I wanna remind you that in the

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classic, um, uh, breast-conserving therapy

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setting, uh, the same thing holds true on MRI as

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holds true on, um, um, mammogram and ultrasound.

1:03

Now, which is that you often have architectural

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distortion in the affected breast.

1:07

You may have seromas as we do in this case,

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this, uh, this breast does have a seroma

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as you may recall from the, um, from the

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T2 images in your gold standard report.

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And also the, um, there's

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usually a size discrepancy.

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Now I must tell you, this is a bad

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example because the left breast

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is actually larger than the right.

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And that is not, as best I

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can tell, because of any

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post-procedural issue.

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The seroma is relatively small.

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But, um, what Dr., um, Dr.

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Lewis submitted this for two specific reasons.

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And one is that the treated breast,

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especially post-radiation, is going

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to have, um, less, uh, background

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parenchymal enhancement for some time.

1:48

It does not classically persist forever

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and ever, but for some period of time.

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And this was, um, this was a newly, uh,

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relatively newly treated breast cancer.

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So for some period of time, um, Uh, be mindful

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and don't over-call background parenchymal

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enhancement in the contralateral breast, okay,

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the normal breast, because that is normal

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background parenchymal enhancement. It's just

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that it's suppressed in the ipsilateral treated.

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And then there's also a nice little example

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right here of a biopsy-proven fibroadenoma.

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Again, I take exception with the fact that

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you have better fibroadenomas in the

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course, and you'll see others of them.

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But remember that a dark internal

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septation in a circumscribed mass that

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is T2 bright and may or may not enhance

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has a very high likelihood of benignity.

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So it's the presence of the

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dark internal septation that

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increases the likelihood of benignity.

2:52

All right, so that's it.

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So the two teaching points for this were VCT

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changes, both anatomically, as well as on

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imaging with the kinetics and the enhancement,

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and then that fibroadenomas that can be seen.

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All right, any questions at all at this point?

3:12

And in which case, I'll just go

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to the final one, and then we can,

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we can talk some more after that.

3:19

Can I just ask something?

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So initially when I looked at this case, I saw

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they were linear, um, it just appeared like

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clumped, like, um, non-mass enhancement.

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But then when I went back to the T2, I thought

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probably it was ductal ectasis and not real.

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Because I thought it was just too diffuse to

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be real, not mass like DCS kind of picture.

3:48

I don't know if you saw.

3:51

Yeah, yeah, no, I, I agree.

3:53

I think, and remember that what you need to

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be looking at are the subtracted images.

3:58

The T1 pre-images sometimes

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have hyperintensity on them.

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And so the fact that there are seemingly hyper-

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intense areas on the T1 post. If they were,

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If they were, if they were T1 pre-bright.

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Uh, not so much the T2, but if they were T1

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pre-write, they're going to subtract out.

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So always remember, honestly, and

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that's my, um, that's my shortcut cue.

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A lot of people say to go to the MIPS.

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But I find that the use of the subtracted

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image, subtracted scroll images, as

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my first diagnostic enhancing image.

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Obviously, I like the anatomy on the, um, pre-

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contrast non-fat sat, but rather than going

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to the MIP first or rather good than going

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to the source data first, I always go to

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the first subtracted for that very reason.

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Um, because I think you get to skip, uh,

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some gnashing of your teeth, um, based on

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what you saw on the non-contrast, pre-image,

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uh, T1 images, and then the post.

5:00

First pass, so I agree.

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I think that's a, I think that was

5:04

a good, very, very nice observation.

Report

HISTORY: High risk screening MRI.
LEFT LOQ breast cancer IDC excised 6 months prior to this exam. Preoperative MRI showed 2 foci of lateral enhancement in the RIGHT breast . Lesion 1 RIGHT breast was a fibroadenoma at US biopsy (UOQ). Lesion 2 was biopsied by MRI guidance and was LCIS (LOQ) which was then excised. Patient status post LEFT breast radiation treatment.

Summary of prior imaging:

Mammography: Post-surgical changes both breasts
Ultrasound: NA
Breast MRI: See above.

FINDINGS

Quality control issues: ☒None ☐Poor/lack contrast bolus ☐Poor fat suppression
☐Susceptibility ☐Movement ☐Other

Background Parenchymal Enhancement: Moderate but asymmetric BPE R>>L
Amount of Fibroglandular Tissue: Extreme fibroglandular tissue

LEFT BREAST

Narrative: 3.5 cm post-surgical seroma with smooth benign peripheral enhancement. No additional lesions.

Left breast lesion 1
Lesion type: Post-surgical change
3.7 cm. Lower outer Quadrant. 7:00 Radian. 6 cm from the nipple

Mass/post-surgical change: Shape:Oval/lobulated. Margins:Circumscribed . Enhancement: Rim. Kinetics: sub threshold
BI-RADS:2: Benign: Routine breast MRI screening if cumulative lifetime risk =>20%

Associated findings LEFT: ☒NONE, ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory, ☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings LEFT: ☒NONE, ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening, ☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions LEFT: X NONE, ☐Fat necrosis, ☐Hamartoma, Post-operative seroma/hematoma with fat

Lymph nodes LEFT: ☒Normal axillary, ☐Abnormal axillary, ☐ Abnormal internal mammary

RIGHT BREAST

Narrative: Post surgical seroma in the RLOQ at site of LCIS excision. Biopsy proven fibroadenoma containing a clip artifact is in the RUOQ. No additional lesions.

Right breast lesion 1
Lesion type: Mass
1.2 cm. Upper outer Quadrant. 10:00 Radian. 3.5 cm from the nipple

Mass/post-surgical change: Shape:Oval/lobulated. Margins:Circumscribed . Enhancement: Homogenous. Kinetics: delayed-Progressive

BI-RADS:2: Benign: Routine breast MRI screening if cumulative lifetime risk =>20%

Right breast lesion 2
Lesion type: Post-surgical change
3 cm. Lower outer Quadrant. 5:00 Radian. 9 cm from the nipple

Mass/post-surgical change: Shape:Irregular. Margins:Circumscribed . Enhancement: Rim. Kinetics: delayed-subthreshold

BI-RADS:2: Benign: Routine breast MRI screening if cumulative lifetime risk =>20%

Associated findings RIGHT breast: ☒NONE, ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory, ☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings RIGHT breast: ☒NONE, ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening,
☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions RIGHT: ☒NONE, ☐Fat necrosis, ☐Hamartoma, ☐Post-operative seroma/hematoma with fat

Lymph nodes RIGHT: ☒Normal axillary, ☐Abnormal axillary, ☐ Abnormal internal mammary

Extramammary findings: None

SUMMARY

LEFT BI-RADS:2: Benign: Routine breast MRI screening if cumulative lifetime risk =>20%
RIGHT BI-RADS:2: Benign

RECOMMENDATIONS: Continue high risk annual screening with MRI and Mammography

Case Discussion

Faculty

Petra J Lewis, MBBS

Professor of Radiology and OBGYN

Dartmouth-Hitchcock Medical Center & Geisel School of Medicine at Dartmouth

Sheryl G. Jordan, MD

Professor, Department of Radiology

University of North Carolina School of Medicine

Ryan W. Woods, MD, MPH

Assistant Professor of Radiology

University of Wisconsin School of Medicine and Public Health

Tags

Women's Health

MRI

Breast

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