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Breast Radiology-Pathology Correlation, Dr. Michael Fishman (07/02/2021)

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Hello and welcome to Noon Conference hosted by MRI Online. In response to

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the changes happening around the world right now and the shutting down of

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in person events, we have decided to provide free Noon Conferences to all

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radiologists worldwide. Today, we are joined by Dr. Michael Fishman. Dr.

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Fishman is a breast imaging radiologist at Boston Medical Center interested

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in artificial intelligence and social determinants of health. Also a trained

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health and wellness coach, he develop both a wellness/non clinical skills

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curriculum and a coaching program for residents. A reminder that there will

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be a Q&A session at the end of the lecture, so please use

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the Q&A feature to ask your questions and we will get to as

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many as we can before our time is up. That being said,

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thank you all for joining us today. Dr. Fishman, I will let you

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take it from here. Hopefully everyone can see my

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slide. Thank you so much for that introduction and welcome to everybody

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who is joining us today from near and far. I encourage you

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just so that I can get a sense of who our audience is,

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feel free to put into the Q&A where you are from and

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whether you are a resident or an attending and

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what specialty you are thinking about going into if you are a trainee or

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a fellow for that matter. So I wanted to talk a little bit

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about Rad Path correlation, which is something that we do in breast imaging

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all the time. Primarily at the time of the biopsy or when we

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get the pathology back, some institutions like our own have a specific Rad

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Path correlation conference that they hold at regular intervals to discuss

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either all biopsy cases or particularly challenging cases where there may

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be an interesting lesson learned. So we are going to just jump into

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it. The goal for today is to talk about

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concordance for benign and malignant diagnoses to identify when discordance

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might be suspected and when there may be additional sampling needed and

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to review management for some areas that are a little bit more controversial

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recently. So just in general, as you hopefully are all aware,

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there are lots of different ways to perform biopsies.

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What we do in radiology is minimally invasive relative to surgery and there

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are lots of different modalities that can guide our images and our procedures.

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Primarily in breast imaging, we use mammography with stereotactic biopsies

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and with ultrasound core biopsies. And there's lots of other procedures

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that have been developed, not specifically for diagnoses per se, but sometimes

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for presurgical planning. The advantages of the core biopsy relative to

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surgery is that they're very accurate in making the diagnosis and

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most importantly, they're able to differentiate invasive from in situ carcinoma,

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which is generally different than an FNA as well as receptor status for

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cancer diagnoses, which help guide treatment. In addition, it's very fast,

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we can do these sometimes as quickly as 10, 15 minutes.

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They're much less costly than surgery, there's less

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pain, there's minimal recovery time for most patients.

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And when we are able to make a diagnosis before surgery,

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it really optimizes oncologic management. And recently, at least at our

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institution, there's been a lot more neoadjuvant chemotherapy being performed.

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And so I'm curious to hear about whether that is happening at your

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institutions as well. So again, lots of different modalities to use,

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most commonly are ultrasound core biopsies. In general, they're more comfortable

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for patients and very fast to perform. So

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what we do is we perform the biopsy, send the tissues to the

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pathologist, and then coming back, we want to look at the diagnosis that

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the pathologist sends us and determine whether or not it is concordant,

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whether it sort of matches up with what we expected on the imaging

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findings. So when we're looking at the imaging, not only do we categorize

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it as suspicious with the BioEds 4 or 5, but we also have

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in our mind a differential diagnosis for whatever lesion it is,

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whether it's a mass or calcifications or an asymmetry, as to what that

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target lesion may or may not represent. So

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we may expect a cancer, and if the diagnosis is not a cancer,

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then it calls into question whether or not the results are concordant.

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So it's important to communicate these findings reliably both from the pathologist

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back to the radiologist and then both from the radiologist back to

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sometimes the referring physician, sometimes the patient, and to addend

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the report with management recommendations. And the documentation is really

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critical in this case. So we're not going to do this poll everywhere,

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but we're going to start looking at some of the cases.

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And the first case is a 41 year old woman who's having her

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baseline screening mammogram. As many of you may know, the American College

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of Radiology recommends screening to begin at age 40 for average risk women.

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In other countries, those recommendations may be different based on

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radiology societies and other medical societies in your countries.

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No other history for this patient. So this patient,

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just to give you a second to look at it, she has heterogeneously dense breast

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tissue. She has calcifications that are in the lower inner quadrant of the

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left breast. So she was called back for workup of those,

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and these are magnification views that were taken at that time.

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And some of these are loose and centered, suggesting that they're dermal

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calcifications, and other calcifications are more coarse heterogeneous.

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Coarse heterogeneous calcifications have a certain connotation. So the question

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is, what is the recommendation for those calcifications? Do we

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think that they're benign and return the patient to screening? Do we think

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they're probably benign and never come back in six months for follow up?

Report

Faculty

Michael DC Fishman, MD

Assistant Professor of Radiology, Section Chief of Breast Imaging

Boston Medical Center

Tags

Women's Health

Breast

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