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Fat-containing Lesions on Tomosynthesis - Overview

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Okay, we're gonna talk about mammographic fat containing lesions. DBT is

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helpful in fat containing lesions because it may reveal the presence of

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fat within a finding which is not apparent on 2D imaging related to

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the overlying dense tissue. However, the presence of fat within lesions

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does not necessarily make the lesion invariably benign. The lesions margins

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also need to be evaluated. DBT allows the assessment of lesion internal

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components and margins and to recognize the, typically, benign encapsulated

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mass. So having that circumscribed margin around a fat containing a mass

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is critical for interpretation. If fat containing and encapsulated, then

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a benign assessment is warranted. Otherwise, additional imaging or evaluation

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or potentially a biopsy is needed. Example, encapsulated fat containing

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masses include lipoma, hematoma, fat necrosis, and galactocele. In terms

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of lipoma, it's typically superficial or intramuscular. It may manifest

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at physical exam and patients may have multiple additional lipomas. This

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can be helpful in your diagnostic setting in the sense where if you're

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evaluating a fat containing lesion, potentially go to ultrasound and you

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talk to the patient and they say, oh yes, I have multiple of

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these all over my body, you can be even more confident that it

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is the imaging finding you're seeing it's probably a lipoma. Typically,

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benign fatty neoplasm, which does not require further imaging, evaluation,

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or follow up, it may be difficult to identify on mammographic exams,

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but it's more classically seen on ultrasound exams. Hematomas are

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also benign circumscribed masses. They contain a very amount of normal appearing

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fibroglandular tissue as well as fat. And this falls into the classic teaching

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of the breast within a breast appearance. It demonstrates a capsule or pseudo

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capsule at mammography. It's usually round or oval, an overall shape.

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Contains a variable normal breast tissue components, fat, glandular tissue

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calcifications. Because they have these glandular components, malignancies

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may develop within a hematoma as well and so they need to be

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closely evaluated as well. Fatty necrosis, of course, we see in a lot

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of screening and diagnostic exams. It has a variable mammographic appearance

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based on the phase of development. You can see an oval or round mass,

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possibly with a fluid level. You may see an overall round fat containing

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mass with associated rim calcification, sometimes called an oil or lipid

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cyst, which is what's demonstrated in this image.

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And additional associated imaging findings of fat necrosis are also possible.

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You may see loose and centered, coarse or dystrophic calcifications or distortion,

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rim like appearance, all those demonstrate are related to fat necrosis.

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Galactocele is obviously most commonly arise in a lactating female secondary

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to entrapped milk arising from a clogged duct. This can be quite large,

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quite numerous, or it can be solitary and small. The imaging appearance

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really depends on the amount of fat and milk contained within.

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You usually see a round or oval circumscribed mass, you can see a

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possible fat fluid level, which is pathognomonic and therefore doesn't need

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any further workup. An ultrasound, of course, is helpful for evaluating

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further internal contents and to distinguish it from something that might

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be like a solid and cystic mass, which would require further evaluation

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of biopsy. Non encapsulated fat containing masses, of course, also exist.

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They can be circumscribed, something like a phyllodes tumor or a papillary

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mucinous or high grade invasive ductal carcinoma can also be seen or potentially

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metastatic disease. Speculated masses and distortion can contain some fat,

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like a radius scar, complex sclerosing lesions, sometimes called that dark

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star appearance. Invasive ductal carcinomas could also present that way

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as well. So the bottom line is that non encapsulated masses or masses

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don't have that thin circumscribed margin and they demonstrate any suspicious

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features should be recommended for biopsy. So if you see any of those

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components, you really need to do some more work to figure out what

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exactly that is. In this case here, we see this mass in the

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left breast at approximately two o'clock position, middle depth, and we

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can see some internal components which have some fat within it.

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So, for example, here and here, but clearly this mass does not have

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a circumscribed margin. This is at least indistinct, possibly obscured.

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You also sort of wonder about some of this density going this direction

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here. And clearly this warrants some further evaluation. That mass was subsequently

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biopsied and was an invasive ductal carcinoma.

Report

Faculty

Ryan W. Woods, MD, MPH

Assistant Professor of Radiology

University of Wisconsin School of Medicine and Public Health

Tags

Women's Health

Tomosynthesis

Mammography

Breast

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