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Larynx - Subglottic Carcinomas: Patterns of Spread & Differential Dx

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Hello everyone.

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Dr. Sidney Levy here, continuing our discussion of the

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diagnosis and staging of laryngeal squamous cell malignancy.

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I'm at the level of the subglottis at the moment.

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I've been using this large transglottic tumor as an

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example for us to see how tumors in this region spread.

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Subglottic tumors tend to spread

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in one of four or five ways.

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There tends to be a pattern of circumferential

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spread, so sometimes all you will see is a

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circle or partial circle of tumor internal to the

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cricoid ring involving only the subglottic mucosa.

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They can also spread in a cephalad fashion to involve

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the true vocal cords or indeed the supraglottis.

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Sometimes they spread anteriorly directly

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through structures such as the cricothyroid

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membrane or the cricotracheal membrane.

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And they can also spread directly posteriorly into

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the cricoid cartilage and the cervical esophagus.

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Lastly, uncommonly, they may also

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spread, uh, inferiorly into the trachea.

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In this case, the tumor is primarily situated

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within the supraglottis and the glottis, and

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the subglottis has been the destination of

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spread rather than the origin of the tumor.

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Last thing to consider is the differential

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diagnosis of subglottic tumors.

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These are glottic tumors, and the best thing to do there

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is to try and identify the level of the commissures and

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the true vocal cords and make an assessment as to whether

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you think the tumor is centered at the level of the

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glottis or below that at the level of the subglottis.

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You can also see conditions as with other laryngeal

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tumors such as, uh, chondroid tumors, chondrosarcoma,

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or autoimmune conditions such as

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rheumatoid arthritis, sarcoidosis.

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Rarely, trauma may be mistaken for a tumor if

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there has been a traumatic event to the larynx.

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Sometimes, uh, the way in which

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that heals can look tumor-like.

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And lastly, minor salivary gland malignancies

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such as adenoid cystic carcinoma can also,

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uh, be present in the subglottis, and often

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this diagnosis is made by the pathologist.

Report

Description

Faculty

Sidney Levy, PhD, MBBS

Radiologist and Nuclear Medicine Specialist

I-MED

Tags

Trauma

Non-infectious Inflammatory

Neuroradiology

Neuro

Neoplastic

MRI

Larynx

Infectious

Head and Neck

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