7 year old with Pre B ALL STATUS post BMT and trisomy 21, altered mental status. Over the past couple days, he had tremors. Patient on Tacrolimus (FK-506).

What is the most likely diagnosis?

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Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Joshua P Nickerson, MD

Associate Professor of Neuroradiology

Oregon Health & Science University

Francis Deng, MD

Assistant Professor of Radiology and Radiological Science

Johns Hopkins University School of Medicine