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Adenocarcinomas – Summary

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There are two varieties of adenocarcinomas I'd

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like to refer you to with regard to the salivary glands.

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The first is that which occurs within the gland

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itself, which is usually occurring in minor

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salivary gland tissue or can occur in the parotid

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gland and this will favor the palate as are most

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of the minor salivary gland neoplasms.

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Its five-year prognosis is pretty poor at only

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46%, and there may be squamous infiltration

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adenosquamous varieties of these carcinomas.

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The second is the salivary ductal carcinoma, which

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is a variety of adenocarcinoma that is again a

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relatively aggressive-looking tumor that can

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infiltrate the glandular tissue

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as well as the ducts.

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Now,

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I had previously shown you a case of squamous cell

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carcinoma of the duct which is thought to be due to

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change in the

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the adenomatous tissue via metaplasia to squamous cell

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and then from squamous metaplasia to squamous

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cell dysplasia and carcinoma. In this case,

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this is an adenocarcinoma affecting

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the salivary gland ductal tissue.

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Here is an example of

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two cases of adenocarcinoma,

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one involving the parotid gland,

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which has that typical dark signal

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intensity on T2-weighted scan.

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So, T2-weighted scan, parotid gland relatively bright,

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that cancer being quite dark,

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and this would probably be one that I would be

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concerned has a high nucleus-to-cytoplasm

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ratio and therefore a low ADC value.

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And here is another one. You're getting used to

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probably seeing the hard palate cancers,

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in this case, an adenocarcinoma grows into the inferior

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aspect of the maxillary antrum

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from the hard palate. Again, rising from minor

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salivary gland tissue of the hard palate.

Report

Description

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Tags

Salivary Glands

Oral Cavity/Oropharynx

Neuroradiology

Neoplastic

MRI

Head and Neck

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