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Tumefactive Sludge

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So this next patient is an 80-year-old gentleman who got

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a CT scan, I believe, for abdominal pain, and they found

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something on this study that then prompted an MRI.

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I want to start off with the CT scan just

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to show you what they were worried about.

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So certainly there's a lot of ductal dilatation you

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can see here that certainly they're worried about,

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but there's another lesion here that I want to

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draw your attention to, and that's right over here.

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I'm going to zoom up on it and I'll show

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it to you in different planes as well.

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You can see here, just at the, uh, beginning

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of the gallbladder, there is this sort of

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soft tissue structure that looks like it's

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protruding into the gallbladder wall over there.

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And so that's something that the

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radiologists saw and they were worried about.

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You can see it once again, perhaps

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nicer on the coronal plane over here.

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I'll zoom up on it for a second,

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and I'm going to window it as well, right over there.

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So certainly there's lots of biliary ductal dilatation.

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That's something that needs to be investigated.

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But in addition to that, there's the

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sort of soft tissue structure that's

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associated with the gallbladder.

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And so, the possibility was brought up that

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this could be something that is neoplastic

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in etiology, for which an MRI was requested.

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So here we have the MRI for the patient.

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I'll start off by looking at the axial, uh, and

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coronal T2-weighted images without fat saturation,

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just to get a sense of what this lesion looks like.

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As we're scrolling downwards,

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we'll see lots of biliary ductal dilatation.

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We're going to try to ignore that for the moment

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and just focus on the gallbladder finding.

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You can see it right over here,

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relatively T2 hypointense.

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And when we see it on the coronal image,

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you can see it as a mass-like lesion that's sort

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of protruding from the mucosal surface of the

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gallbladder into the gallbladder lumen itself.

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And we can look at the gallbladder in the T2 fat

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saturated image just to get a sense of what this

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lesion looks like on another T2-weighted sequence.

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It looks very, very hypointense over here.

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on the pre-contrast images.

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It's a little tough to figure out the actual signal

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intensity of this lesion because the gallbladder

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itself is filled with T1 hyperintense content.

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It's a little tough to see what it looks like

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here, but as much as we can see, it looks

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pretty hypointense, at least centrally,

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on the T1-weighted images without contrast.

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And we give contrast and jump right into the

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subtraction images to sort of eliminate all that

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hyperintense content within the gallbladder itself.

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So here we have our T1-weighted fat-saturated

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post-contrast sequence with subtraction.

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I'm looking to see if this little lesion here enhances.

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And as you scroll through it, it looks like

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there is, uh, pretty much a signal void.

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It looks hypointense throughout the gallbladder,

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and certainly in that region, uh, the expected, uh,

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mass itself, you can kind of see a little bit of it

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here, but there's no internal enhancement within it.

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So essentially, we have a mass-like lesion

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that's protruding into the gallbladder

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that's relatively hypointense in all imaging

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sequences that shows no enhancement, and, uh,

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you know, this appearance is quite 73 00:03:06,200 --> 00:03:07,600 characteristic of what we

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call, uh, tumefactive sludge.

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And the word tumefactive is used to

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describe it as a sludge that looks a

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little bit more mass-like or tumor-like.

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But indeed, it's not a tumor because it

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doesn't have any enhancement within it.

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It's important to know what it looks like

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because it could be mistaken for a tumor,

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particularly when you don't have the appropriate

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imaging to really figure out what it is.

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Signal within tumefactive sludge can be variable.

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In this case, it was hypointense.

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But I think the key finding here is that when you give

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contrast, this lesion over here does not enhance.

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When it does not enhance, it's very

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reassuring for tumefactive sludge.

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There's nothing that needs to be done about it.

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It's just sludge that looks a little bit more

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mass-like than normal sludge, which

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typically has that sort of layering effect

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along the dependent portions of the gallbladder.

Report

Faculty

Mahan Mathur, MD

Associate Professor, Division of Body Imaging; Vice Chair of Education, Dept of Radiology and Biomedical Imaging

Yale School of Medicine

Tags

Non-infectious Inflammatory

MRI

Idiopathic

Gastrointestinal (GI)

Gallbladder

Body

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