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Ciliated Hepatic Foregut Cyst

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This next case is a, uh, 30-year-old female

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who presents with right upper quadrant pain.

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An ultrasound was performed showing, uh, an

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indeterminate liver mass for which an MRI was ordered.

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So here we have the axial, uh, T2-weighted

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image, and we can see immediately a lesion

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bordering the right and left hepatic lobes.

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This can also be seen on the coronal image over here.

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And so we look at our, uh, T2-weighted image, we see the

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lesion here bordering the, uh, right and left hepatic lobes.

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Looks, uh, pretty well-defined, round and oval in shape.

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And the content of it is certainly T2 hyperintense

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for the most part, certainly the cephalad aspect of it.

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But there is a discrete layer over here, and internally

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below it, it is hypo to intermediate in signal.

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So it looks a little bit darker than CSF over there.

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And we notice that its location is out at the

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periphery. And is almost subcapsular in this location.

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That becomes a very important descriptor of this lesion.

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We can see it again here on the coronal images.

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As we scroll through the remainder of the case, we can see

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that there's not a whole lot of other cysts in this patient.

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Only that one sort of isolated cyst, bordering the

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right and left hepatic lobe, subcapsular in location.

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There is another mass over here, which turns

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out to be a different entity, and not a cyst,

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which we're not going to talk about now.

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But this is the only finding that we see.

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that looks, uh, cystic in its appearance.

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So we'll look at this systematically.

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Moving on with our T1 in and out of phase images.

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So here we have the T1 in and out of

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phase images to evaluate this lesion.

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On the out of phase image over here, we can

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see that the mass, uh, is T1 hypointense.

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On the in-phase image over here, we

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can see it's also T1 hypointense.

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There's no areas of signal loss on

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the out of phase image to suggest fat.

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And there's no areas of signal loss in the in-phase

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images to suggest areas of increased susceptibility.

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Move on to our T1 pre-contrast fat-saturated images.

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And over here, we can again see that the

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mass is pretty well-defined, relatively

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hypointense on these T1-weighted images.

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Um, and looks pretty otherwise simple, but we're

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going to have to give intravenous contrast to

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make sure that there's no internal enhancements.

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So here we have the T1 dynamic post-

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contrast imaging sequences and let's have

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a look and see what this lesion does.

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And the arterial phase images remains avascular,

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pretty well-defined, similarly on the portal venous

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phase images and the equilibrium phase images.

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Looks, uh, pretty much like a simple cyst.

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Going back to our T2-weighted images, again,

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um, in all the imaging phases, this pretty much

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looks like a simple cyst, but there is probably

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a little bit of debris layering within it.

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So, why am I discussing this particular case?

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And the reason is because there is a very uncommon

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entity called ciliated hepatic foregut cyst.

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So, a ciliated hepatic foregut cyst

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that, as mentioned, is very uncommon.

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It's usually unilocular, about three centimeters in size.

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On imaging it can have a little

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bit of a debris level like this.

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And it has a very characteristic location

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that is often subcapsular and in segment four.

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This happens to be probably bordering four

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and eight, but close enough to segment four.

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It tends to happen more commonly in

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male patients who are middle-aged.

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And it can present with right upper quadrant

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pain because of that subcapsular location.

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It can stretch the liver capsule over

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here if it gets a little bit larger.

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And it You know, I sort of suggest this entity in

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instances when a patient comes in with pain, right

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upper quadrant pain, no other findings, demographics

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are pretty reasonable, and it's an isolated cyst.

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Often with these lesions, the lesion

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is isolated, as seen in this case.

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If you look at patients who have liver cysts,

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often they'll have more than one cyst in the liver.

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They won't have 10 or 20.

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As seen with polycystic liver disease, but they'll

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have a scattering of, say, two or three cysts.

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With this entity, it's often isolated,

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subcapsular, segment four it can cause pain.

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So why is it a big deal?

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The reason is, is that there's about a

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3% risk of malignant transformation.

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And when that happens, it goes to squamous cell cancer.

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And so if we're gonna think about this entity,

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uh, we have to let the surgeons know about it.

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They can go ahead and potentially resect it, uh, in time.

Report

Faculty

Mahan Mathur, MD

Associate Professor, Division of Body Imaging; Vice Chair of Education, Dept of Radiology and Biomedical Imaging

Yale School of Medicine

Tags

Ultrasound

MRI

Liver

Idiopathic

Gastrointestinal (GI)

Congenital

Body

Acquired/Developmental

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