Interactive Transcript
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This next patient is a 60-year-old female who has a
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history of cirrhosis and presents for surveillance MR
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imaging in order to look for hepatocellular carcinoma.
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So we'll start off with our T2-weighted sequences in order
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to evaluate any potential liver lesions in this patient.
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As you scroll through it, we do see
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a lesion in the left hepatic lobe.
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On the T2-weighted sequence performed without
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FATSAT, you can see the lesion right over here.
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It's mildly T2 or hyperintense.
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And the T2 hyperintensity is certainly not as bright
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as CSF, and it's not as bright as some of the other
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things we've seen so far, other hemangiomas we've
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seen so far, and certainly not as bright as the cyst.
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On the T2-weighted sequence performed with FAT SAT,
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the treble spin echo sequence, this is the one where
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we're really going to scrutinize the T2 signal.
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And once again, it is hyperintense, but not as
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bright as some of the other lesions we've seen.
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Another thing that I want to point out is that which will
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become relevant in this case is, granted the liver has
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a quite nodular contour compatible with cirrhosis.
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But as you start to approach this lesion,
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you can see a very discrete area of capsular
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retraction over here and over here.
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And we'll come back to that later on in this case.
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The next set of images are the T1s in and out of phase.
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We'll see how this lesion looks like on these images.
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And the out-of-phase sequence over here, the lesion's
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a little bit tough to pick up, but there it is.
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Slightly, slightly T1 hypointense on this image.
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On the in-phase sequence, again, a little bit,
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uh, tough to see, but remains T1 hypointense.
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We don't see any fat within it on the out-of-phase sequence.
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We don't see any signal drop on the in-phase sequence.
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This suggests it contains any content that
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can result in increased susceptibility.
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Once again, if we follow the liver border, we can
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note that that, there is that discrete area of
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capsular retraction that's associated with this mass.
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is the T1 FATSAT pre-contrast sequence.
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And on this sequence, the, uh, pre-contrast FATSAT, we
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can see the lesion again, mildly T1 hypointense, capsular
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traction associated with over here, and the key then is
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going to be, what does it look like when we give contrast?
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So we'll move on to our post-contrast dynamic images,
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and we can see the lesion right here in the left hepatic
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lobe, showing some, uh, enhancement with contrast.
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On the arterial phase images, it demonstrates
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pretty much continuous ring enhancement.
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We're seeing enhancement surrounding
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the entire portion of this lesion.
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On the portal venous phase, the lesion becomes a little
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bit tougher to see, but it still sort of has that ring
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enhancement potentially, potentially some of that ring
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enhancement is filling in a little bit as the central
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portion of this lesion becomes less conspicuous.
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And on the equilibrium phase images, again,
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demonstrates pretty much ring enhancement
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and potentially that central portion is less
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conspicuous than seen on the arterial phase images.
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So here we have a mildly T2 hyperintensive lesion with
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sort of continuous ring enhancement that maybe fills in.
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It's associated again with this capsular retraction
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and as such it remains an indeterminate finding.
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But one of the things you have
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to think about in this instance.
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is this entity of a sclerosed hemangioma.
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Now these are uncommon entities, and they result
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when the vascular channels within the hemangioma,
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for whatever reason, undergo thrombosis.
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And so these hemangiomas look a little bit
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more different than your typical hemangiomas,
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the hemangiomas that we've covered so far.
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They are, um, characterized by, um, sort of
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mild T2 hyperintense signal, So, Sometimes
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this sort of ring enhancement that fills in.
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But typically, these, when they're associated, uh, out
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in the periphery of the liver, have capsular retraction.
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capsular retraction, one of which could be a
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malignant entity, such as a cholangiocarcinoma.
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However, cholangiocarcinomas, as you go from the
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arterial to the portal venous to the equilibrium
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phase, their contrast gets a lot brighter.
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It looks brighter on that image.
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In this instance, this contrast doesn't get
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brighter, and if anything, follows the blood pool.
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So that's why we're going to think that
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this could be a sclerosed hemangioma.
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However, the definitive way to make this
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diagnosis is really one of two ways.
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You can either biopsy it, or if you're lucky enough to
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see if the patient had prior imaging, we can hopefully
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look at that to see if the patient had a lesion in this
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location that looked like a more typical hemangioma.
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Now in this instance, we were lucky enough to have imaging
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from a couple of years prior that looked at this lesion.
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And so we'll look at it quickly in our T2-weighted images.
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We can see that it looks a little bit larger on the
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prior MRI study, seen here on the T2 fat-saturated image.
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And I think the T2 signal within
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this is nicely seen on the sequence.
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It's relatively bright on the T2
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weighted fat-saturated sequence.
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We'll do our due diligence and look at the in and out
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of phase sequences to make sure this lesion doesn't
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contain any fat or areas of susceptibility artifact.
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We can see this lesion here, T1 hypointense on the out
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of phase image, T1 hypointense on the in phase image.
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And then we'll move right along to the dynamic
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post-contrast images, where we can see this lesion
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once again in the left hepatic lobe, demonstrating
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imaging features of a more typical hemangioma.
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So in the arterial phase, we can see it once again
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over here, demonstrating this sort of peripheral
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discontinuous puddling of contrast on the portal
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venous phase images, a little bit tougher to see.
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contrast starts to fill in, and even harder
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to see on the equilibrium phase images.
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The fact that it's harder to see on these images tells
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us that it's filling in on the subsequent phases.
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So, we were able to diagnose this as a sclerosed hemangioma,
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a benign entity in this patient with a history of cirrhosis.
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