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Portal Hypertension – 2 Patient Case Review

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The following are two different patients with

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cirrhosis, both of whom have imaging features

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of portal hypertension, which is what we're

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going to showcase in this video vignette.

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So as we scroll through these

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images, both of which are T2-weighted

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sequences performed without fat

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saturation in two different patients.

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In this patient, you can see that

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there's a lot of ascitic fluid.

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And so patients with portal hypertension

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will often see varying amounts of ascites, so

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that's one of the features that you should look

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for, and one of the features that you should

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comment on, whether it's a small amount, a

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moderate amount, or a large amount of ascites.

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We can see more ascites over here and

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over here in the left upper quadrant.

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In this other patient over here,

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we can see other features of portal

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hypertension, namely splenomegaly.

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Splenomegaly.

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It's measured typically in the cranial

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caudate dimension, so I like using

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coronal sequences to measure it.

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And anything above 13 centimeters is

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generally considered too big for the spleen.

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Another feature that can be seen with the

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spleen is the presence of gammaglobulins.

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And this is nicely demonstrated

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in this patient over here.

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This is a T1-weighted sequence

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performed out of phase, no contrast.

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This is a T1-weighted sequence.

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Performed in phase, no intravenous contrast.

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And if we look at the spleen, we can see

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that there are multiple tiny splenic nodules.

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For example, we'll showcase this one over here.

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In the out-of-phase image, it looks pretty dark.

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And on the in-phase image, it looks larger.

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Now the size itself is not changing, but it's

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demonstrating a blooming artifact that can be

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seen with what we call gammaglobulin bodies.

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These are little siderotic nodules, little

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iron-containing nodules essentially that

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can be seen in the spleen, um, particularly

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in the setting of portal hypertension.

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Another feature to look for in patients with

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cirrhosis, and you're looking for signs of

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portal hypertension, is the presence of varices.

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So this is a T1-weighted sequence

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performed with intravenous contrast,

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done in the portal venous phase.

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And you can see surrounding the esophagus

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over here that there are multiple

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serpiginous enhancing structures.

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These are all going to be varices,

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parasophageal varices in this patient who has

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cirrhosis and signs of portal hypertension.

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And yet another place that you're going

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to look for signs of portal hypertension is

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typically in that intersegmental fissure.

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With portal hypertension, you can get

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a recanalized paraumbilical vein.

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So this is just a version of

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a portosystemic shunt that develops

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because of the portal hypertension; blood

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gets siphoned through this collateral

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vessel, goes into the anterior abdominal

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wall, and drains into the systemic

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vasculature before going back to the heart.

Report

Faculty

Mahan Mathur, MD

Associate Professor, Division of Body Imaging; Vice Chair of Education, Dept of Radiology and Biomedical Imaging

Yale School of Medicine

Tags

Vascular

Non-infectious Inflammatory

MRI

Liver

Gastrointestinal (GI)

Body

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