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Wk 3, Case 5 - Review

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Her history was a 35-year-old high-risk

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female presented with a calculated

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lifetime risk of 32%.

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In the states and by American Cancer

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Society, um, white paper way back

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in 2007, but it hasn't changed.

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Anybody with a calculated lifetime risk

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above 20 percent is in fact eligible

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for, um, high-risk breast cancer,

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uh, breast MR, uh, cancer screening.

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So we, um, I, um, the anatomy

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is not the T1 pre or not pre.

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Are not particularly helpful in this

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case, although it is a lovely example.

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I'll show it to you.

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It's a lovely example of bad field of view.

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You should not have more than half of

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your screen occupied by the air in front

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of the patient or in this case beneath.

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Remember, these are prone in the air around

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the patient and the lungs themselves.

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So this is a, it is a nice example.

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The T1 pre's of, um, of, uh.

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Uh, bad field of view.

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Um, it's also a really nice

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example of dense breast.

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So I do think the T1 pre's again, I don't

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mean to be focused on them wholly, but

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the T1 pre non-fat set give you a really

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nice estimation of the breast, the amount

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of breast parenchyma, the breast density

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analog, and that is required in all reports.

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At least here in the States.

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Okay.

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So, that being said, you can also also

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get a hint already of what a problem is

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going to be in this case, which is that

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her breasts are seemingly quite asymmetric.

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It's not the case, but that they

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certainly are projecting asymmetrically.

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So, then I'm going to go on now

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to the subtracted image.

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Part of the reason I'm going to go

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over this in the manner that I am.

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Oh, 1 more thing.

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One more thing for the A relatively newer MR.

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48 00:01:47,770 --> 00:01:50,500 interpreter get to know what machine

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and or what platform is going to be

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presented to you and work through

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that or rearrange that to your liking.

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From my perspective, I find it much easier

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to, um, to assure that my images are

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flipped anatomic, as if I'm reading a CT

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or other cross-sectional imaging, and if

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I, as if I am, um, uh, starting at the,

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at, uh, cranial and scanning caudate.

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Other people, uh, many platforms actually

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scan from, um, bottom to top and, um, display.

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Prone, but I assure that each time I

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review, um, I'm reviewing in that manner.

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And so this is the way we're going to review it.

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This is anatomic and we're starting at the top.

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This case stumped many of you.

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I've already corrected your case 3

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submissions and uploaded them to Olivia, but.

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This case seemed to stump most of you actually.

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And so I just wanted to point out that

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there was a lot of focus on this, um,

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apparent non-mass enhancement bilaterally.

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Um, and let's go ahead and

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just dispense with that.

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This is normal picture framing.

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It's very pronounced in this case, and it is,

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um, oddly asymmetric, which can definitely

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be, um, the confusing and confounding.

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Um.

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Uh, which is kind of all the more reason

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I was happy that we had, um, at the

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time of my, um, learners had read it

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out at UNC wrongly and had read it

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as diagnostic and had called her back.

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Well, or had called it by rights

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for as did many of you, by the way.

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So, um, welcome to breast, breast fellowship,

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I suppose, because that's exactly how it was

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read by our fellows and upper-level residents.

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But, um, the, the thing that's actually

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more important and of significance

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is that you can tell that the coil

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is actually pinching the left breast.

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The nipple is not dangling freely.

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It's not positioned symmetric

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with the right side at all.

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And so, honestly, the impingement

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of the coil related to

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breast placement in the coil may be exactly

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why, um, it looked like it was asymmetric.

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And it may when in point of fact,

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it's just normal picture framing.

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And so there are three points

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I want to make about this case.

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Um, number one, we want to emphasize

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the need for correct positioning.

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The breast should be as symmetric, especially

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if they are not post-therapy in any manner or

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have not been surgically altered in any manner.

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And this was a young woman

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who had never had surgery.

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And so she was just, she should

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have been positioned symmetrically

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and should look symmetric.

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And, as you know, in the follow-up

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scan that we did on her, she did those

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images, I think, have already been

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provided to you the field of view issue.

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There's just nothing but air gap and

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wasted information from here from here up.

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Uh, and from here down on each image

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that I realize that's not anatomic the

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way she was positioned, but and then

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lastly, the picture framing and, um, let

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me just remind you what picture frame.

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It's a great, um, it's a great and very

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common, particularly in young patients, um,

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in young patients, uh, high-risk screening MRI.

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R.

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S.

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So the, um, so it is a form of, um,

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background parenchymal enhancement.

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It relates to the normal

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arterial inflow of the breast.

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It is at the periphery of the breast,

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and because of the way many breasts are

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scanned, um, it just so happens that either

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the superior quadrants or the inferior

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quadrants will be the ones that asymmetrically

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fill in from the periphery.

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It is also true that both inferiorly

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and superiorly the breast,

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fill in from the periphery.

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And so in some instances, you really

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do have a bonafide picture frame,

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and in other instances, as in this case,

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um, you kind of have to use

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your imagination. But you begin to see,

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in particular, um, two sides of a picture frame,

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and particularly if you saw it on the left

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side, um, as well, which you probably would

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have, were it not for the fact that the coil

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is pinching her and, um, impeding inflow.

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I don't think it would have

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stumped as many of you as it did.

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We would have had far fewer indicators

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as abraded for the right breast had the

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left breast been appropriately positioned.

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And so in essence, it's a benign pattern of vascular inflow.

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Enhancement is a type of

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background parenchymal enhancement, but

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it is very specifically called

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picture framing, and it must indeed be

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distinguished from a non-mass enhancement.

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So that's it.

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Those are the 3 teaching points for this case.

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I'll just, in terms of time, refer you back to

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part 2 of this case.

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So this should be a byproduct.

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Excuse me, technical repeat hardly ever

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have byproduct zeros in breast.

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We don't use them at all when the

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study is deemed to be diagnostic,

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but additional imaging is needed.

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But in this case, it was a repeat

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technical repeat that was needed.

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And so that's it.

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So, positioning, field of view, and one.

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Any questions?

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Just a quick question

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about the, um, about the technical repeat.

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That was because of the positioning, not

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because of the picture framing, correct?

7:34

Correct.

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That was because of field

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of view and positioning.

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Honestly, more positioning and

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pinching and impeding of the left

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breast than the field of view.

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I think honestly, I think he

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can work around field of views.

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It's annoying, and you know, you have

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to reframe virtually every sequence

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to assure that you get that distracting,

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detracting black around it out of the

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way by zooming all of the sequences.

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It's annoying, but it's not,

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it doesn't, it doesn't pose a barrier

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per se to the to the to the MR.

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201 00:08:08,820 --> 00:08:11,950 Imaging itself, whereas the impingement

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of the left breast and, um, and, um, how,

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um, oddly, um, oddly positioned it was

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and also the impingement of enhancement

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or the possible impingement of enhancement

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in the left breast reduces the sensitivity

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of, um, screening for that left breast.

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That makes sense.

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Yes, thank you.

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Okay.

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Yeah.

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Yeah.

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These are great.

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Am I, um, am I at a clip and at a, uh,

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is this to the participants liking?

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Is this to the scholars' liking?

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I mean, that's my main question.

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I'm here to serve you and.

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I want to make sure that I'm

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speaking clearly, that I'm covering

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topics that you think are germane.

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There are several.

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Oh, one thing.

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I didn't want to say there are several

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positioning and other technical issues

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that you should familiarize yourself with.

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And the great news is that

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they are so it's so easy.

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There are two, these are all these book goodies.

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There are two radiographics articles

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that are, um, that are commended to

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you at the end of the gold standard

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report for Case 5 to Radiographics.

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They're both in 2007.

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Active links were provided

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to, um, to all of you.

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And so one is Jen Harvey's, you know, she's

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a dean now, her article, and one is Mary Mary

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Mahoney, who is a chair now, her article.

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So there are two of them.

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The references are numbers 1 and 4.

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That are listed on the gold standard and

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honestly, I don't even think you need

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to read the articles, but by all means,

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pick the Radiographics articles up.

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And they are, as you all, as you

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all probably know, um, uh, designed

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to have, um, good illustrations.

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And so most of the issues and how to

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solve them are very well illustrated.

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So I commend those two to you.

Report

HISTORY: 35 year old high risk woman presented with calculated lifetime risk 31.9%

Summary of prior imaging:

Mammography: Extremely dense breasts, negative
Ultrasound: None
Breast MRI: Normal

FINDINGS

Quality control issues: ☒None ☐Poor/lack contrast bolus ☐Poor fat suppression
☐Susceptibility ☐Movement ☒Other – positioning and field of view

Background Parenchymal Enhancement: Mild
Amount of Fibroglandular Tissue: Extreme fibroglandular tissue

LEFT BREAST

Narrative
There are no suspicious enhancing masses or areas of non-mass enhancement. No axillary or internal mammary lymphadenopathy is seen. There is no abnormal skin, nipple, or pectoralis muscle enhancement.

Left breast lesion 1
Lesion type: Choose an item.
Longest measurement cm. Choose an item Quadrant. Choose an item. Radian. dist from nipple cm from the nipple

BI-RADS: 1: Negative: Routine breast MRI screening if cumulative lifetime risk =>20%

Associated findings LEFT: ☒NONE, ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory, ☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings LEFT: ☒NONE, ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening, ☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions LEFT: ☒NONE, ☐Fat necrosis, ☐Hamartoma, ☐Post-operative seroma/hematoma with fat

Lymph nodes LEFT: ☒Normal axillary, ☐Signal void from clips, ☐Abnormal axillary, ☐ Abnormal internal mammary

RIGHT BREAST

Narrative
There are no suspicious enhancing masses or areas of non-mass enhancement. No axillary or internal mammary lymphadenopathy is seen. There is no abnormal skin, nipple, or pectoralis muscle enhancement.

Right breast lesion 1
Lesion type: Choose an item.
Longest measurement cm. Choose an item Quadrant. Choose an item. Radian. dist from nipple cm from the nipple

BI-RADS: 1: Negative: Routine breast MRI screening if cumulative lifetime risk =>20%

Associated findings RIGHT: ☒NONE, ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory, ☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings RIGHT: ☒NONE, ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening, ☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions RIGHT: ☒NONE, ☐Fat necrosis, ☐Hamartoma, ☐Post-operative seroma/hematoma with fat

Lymph nodes RIGHT: ☒Normal axillary, ☐Abnormal axillary, ☐ Abnormal internal mammary

Extramammary findings: None

SUMMARY: Inadequate study

LEFT BI-RADS: 0: Incomplete: Recommend technical repeat

RIGHT BI-RADS: 1: Negative: Routine breast MRI screening if cumulative lifetime risk =>20%

RECOMMENDATIONS: Technical repeat due to positioning and FOV

Case Discussion

Faculty

Petra J Lewis, MBBS

Professor of Radiology and OBGYN

Dartmouth-Hitchcock Medical Center & Geisel School of Medicine at Dartmouth

Sheryl G. Jordan, MD

Professor, Department of Radiology

University of North Carolina School of Medicine

Ryan W. Woods, MD, MPH

Assistant Professor of Radiology

University of Wisconsin School of Medicine and Public Health

Tags

Women's Health

MRI

Breast

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