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Wk 4, Case 1 - Review

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This is a patient who's had a history of right

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sided breast cancer status post lumpectomy,

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nodal excision, and radiation treatment.

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So I'm going to start here

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with the T1 pre FATSAT images.

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Now there's not, not everybody

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does this as a sequence.

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Um, if you don't do this as a sequence,

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I would highly recommend that you do.

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Um, it has a number of things

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it's really useful for.

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One is it's probably the best anatomy image.

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Um, it's also really good for looking for

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fat necrosis, as we'll see in this patient.

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It's good for looking for fat in lymph nodes

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and it'll get you out of a lot of trouble.

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So I highly recommend it.

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So the first thing that's very obvious on

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this is that the treated breast, the right

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breast, has very extensive skin thickening.

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Um, that right breast appears larger

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than the left, despite the fact that this

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is, um, the patient has had radiotherapy

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on this side and surgery on this side.

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So, you know, that's a little bit unusual.

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Um, probably a little bit of

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trabecular thickening as well.

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Um, while I'm on the T1, um, pre FATSATs.

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If you look down here at the

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lumpectomy site, we have fat necrosis.

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So this has pretty extensive fat necrosis here.

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Uh, and we'll see that on the

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subsequent slices as well.

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So, you know, very nice, um,

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internal fat in this area.

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Um, when we come up to the axilla, we

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have some, uh, we'll look at those on

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the T2, actually, they'll be better.

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We're going to ignore the left breast

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because the left breast is normal.

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The next most important slice on this, uh,

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sequence for this patient is going to be the T2.

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Um, again, always make sure you look at

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the T2 and you can see on the T2 that

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this, um, thickened skin is very edematous.

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There's some edema within the breast,

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but particularly edematous skin.

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Uh, we come up, the fat necrosis doesn't

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really have any increased T2 signal.

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Um, this is the, uh, central node,

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uh, resection site here that we're

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seeing up in the right axilla.

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So it's a big breast.

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It's edematous, and it's got skin thickening.

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Here are the CAD images for the

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first post-injection sequence.

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And what we're seeing here is that

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despite that skin being so thickened,

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there is no enhancement in it.

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There's also no enhancement in the

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surrounding, um, around that fat necrosis.

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And I wish I could show you that.

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So you see on the MIP here, we've got,

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um, fairly, um, significant background

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parenchymal enhancement within the

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breast parenchyma bilaterally, but we're

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seeing no enhancement in that skin.

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So this is a patient who has lymphedema.

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Um, whenever you see skin thickening, we're

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going to be looking, our differential is going

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to be, um, you know, inflammatory breast cancer,

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which is what we always worry about, in which

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case we're going to see enhancement of the skin.

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And I think you haven't

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had a case of that already.

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There is a case of it somewhere in the series.

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Um, edema and lymphedema.

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So edema can be due to cardiac failure,

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for example, which is usually symmetrical.

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Lymphedema, which is obviously asymmetrical.

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Um, I've seen lymphedema both in

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surgical candidates like this, who've

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had lymphatic resections, usually,

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um, total axillary resection, but we

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do see it in central node resections.

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Um, and I've also seen it in

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patients who have extensive

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lymph node disease in the axilla,

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producing edematous breast from lymphedema.

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Um, patients with acute mastitis,

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um, same as on a mammogram, can really

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fool you into thinking they've got

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inflammatory breast cancer and vice versa.

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You're going to have enhancement

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within the breast and within the skin.

Report

HISTORY: 55-year-old woman with a history of right breast lumpectomy and axillary surgery and left breast reduction presenting with a 6 month history of diffuse right breast swelling.

Summary of prior imaging:

Mammography: Recent diagnostic mammogram demonstrates postoperative findings in the right breast, and diffuse skin thickening.
Ultrasound: Ultrasound of the right breast demonstrates skin thickening and no underlying abnormality.
Breast MRI: NA

FINDINGS

Quality control issues: ☒None ☐Poor/lack contrast bolus ☐Poor fat suppression
☐Susceptibility ☐Movement ☐Other

Background Parenchymal Enhancement: Mild Amount of Fibroglandular Tissue: Scattered fibroglandular tissue

LEFT BREAST

Narrative: There are postoperative findings compatible with the clinical history of breast reduction. There is no suspicious enhancement or lymphadenopathy.

Associated findings LEFT: ☒NONE, ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☐Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory, ☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings LEFT: ☐NONE, ☐High ductal signal pre contrast T1, ☐Cyst(s),☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening, ☐Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions LEFT: ☐NONE, ☐Fat necrosis, ☐Hamartoma, ☐Post-operative seroma/hematoma with fat

Lymph nodes LEFT: ☒Normal axillary, ☐Abnormal axillary, ☐ Abnormal internal mammary

RIGHT BREAST
Narrative: There is a 6.8 cm (CC) fat containing mass in the right breast at the 8-9 o’clock position, a finding most compatible with postoperative fat necrosis. There are postoperative findings in the right axilla compatible with prior axillary dissection. There is diffuse skin thickening throughout the right breast. There is no suspicious enhancement or
lymphadenopathy.

Associated findings RIGHT breast: ☐NONE, ☐Nipple retraction, ☐Nipple involvement, ☐Skin retraction, ☒Skin thickening, ☐Skin invasion-direct, ☐Skin invasion-inflammatory, ☐Pectoral muscle invasion, ☐Chest wall invasion, ☐ Architectural distortion

Non-enhancing findings RIGHT breast: ☐NONE, ☐High ductal signal pre contrast T1, ☐Cyst(s), ☐Hematoma/seroma, ☐Post therapy skin/trabecular thickening,
☒Non-enhancing mass, ☐Architectural distortion, ☐Signal void from clips

Fat containing lesions RIGHT: ☐NONE, ☒Fat necrosis, ☐Hamartoma, ☐Post-operative seroma/hematoma with fat

Lymph nodes RIGHT: ☐Normal axillary, ☐Abnormal axillary: description, ☐ Abnormal internal mammary: description

Extramammary findings: None

SUMMARY: Benign postoperative findings in the right breast compatible with prior lumpectomy and axillary dissection. There is diffuse skin thickening throughout the right breast. Given the finding of right axillary dissection, this finding is most compatible with lymphedema.

LEFT BI-RADS: 2: Benign: Routine breast MRI screening if cumulative lifetime risk =>20%
RIGHT BI-RADS: 2: Benign: Routine breast MRI screening if cumulative lifetime risk =>20%

RECOMMENDATIONS: Clinical follow up for right breast lymphedema is recommended. Also recommend routine screening mammography.

Case Discussion

Faculty

Petra J Lewis, MBBS

Professor of Radiology and OBGYN

Dartmouth-Hitchcock Medical Center & Geisel School of Medicine at Dartmouth

Sheryl G. Jordan, MD

Professor, Department of Radiology

University of North Carolina School of Medicine

Ryan W. Woods, MD, MPH

Assistant Professor of Radiology

University of Wisconsin School of Medicine and Public Health

Tags

Women's Health

MRI

Breast

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