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Case: Glioblastoma

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Patients with masses in their brain will

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also present with new neurologic deficits,

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and/or headaches, and/or seizure disorders.

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This was a patient who presented as

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an individual with a new hemiparesis.

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As you can see, there is this mass, which is located

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in the medial right frontal and parietal lobe,

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spanning the expected location of the motor strip.

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If we look on our diffusion-weighted imaging, B0, and

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then our B1000, we do not see bright signal intensity,

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and therefore, we conclude this is not due to a stroke.

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What we are seeing with this very dark

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signal intensity is hemorrhage in the brain.

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And if we were to proceed with our susceptibility

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weighted scan, we would identify that

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this was indeed a hemorrhagic lesion.

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Here's the T2-weighted scan, which is also demonstrable

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for the presence of the hemorrhage within this

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mass, represented by the dark signal intensity.

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This dark signal intensity is deoxyhemoglobin.

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On the post-contrast scan, when we get up to the

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lesion, we see that there is peripheral enhancement

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in this lesion, as well as solid enhancing portions.

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This mass abuts on the falx, posteriorly,

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and therefore, you might wonder, is

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this an intraaxial or extraaxial lesion?

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And the coronal doesn't help us all that much,

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because there's both a portion that's abutting on

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the falx as well as projecting into the parenchyma.

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This patient went to surgery.

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This was a glioblastoma.

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A high-grade astrocytoma that had infiltrated to

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the surface of the brain and even to the falx.

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So, brain tumors, be it metastases or

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be it primary brain tumors, may also

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present with a new neurologic deficit.

Report

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Tags

Vascular

Neuroradiology

MRI

Emergency

Brain

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