0:00

Endophthalmitis or inflammation of the globe can occur

0:06

outside the setting of trauma and foreign bodies.

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Usually, this is secondary to skin infections,

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sometimes affectionately known as Zit Popper syndrome,

0:19

and that is if one has an infection of the skin related to

0:24

acne or other scratches, or perforations of the skin,

0:31

it may extend to the globe.

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Endophthalmitis, as I described earlier,

0:38

is a serious infection and is treated aggressively by the

0:42

clinicians because of this phenomenon in which one

0:45

can have an autoimmune attack on one's own globe,

0:49

leading to Phthisis bulbi.

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Phthisis bulbi is the end stage of either

0:56

trauma or infection to the globe,

0:59

in which the globe is calcified, shrunken, and the patient

1:05

is blind. That autoimmune reaction to the globe may

1:16

was not traumatized or otherwise infected.

1:21

Another inflammatory condition that occurs and

1:24

causes an endophthalmitis is pseudotumor,

1:28

also known as idiopathic orbital inflammation,

1:32

or nonspecific idiopathic orbital disease. In this case,

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one sees asymmetrical enhancement along the posterior

1:43

aspect of the left globe, as well as

1:47

in the adjacent fat soft tissues.

1:52

This would be called scleral or episcleritis.

1:56

Pseudotumor or idiopathic orbital inflammation can

1:59

occur in any part of the globe.

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In this case, one also sees that the sclera anteriorly

2:08

shows greater enhancement than on

2:12

the contralateral normal side.

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Pseudotumor of the orbit is treated with corticosteroids

2:24

as the first line of treatment,

2:26

and therefore, it is important to make

2:28

the distinction between an infection,

2:31

which should not be treated with steroids,

2:33

and this idiopathic orbital inflammation,

2:36

which is treated with steroids.

2:38

Both of these types of diseases can cause

2:43

pain and tearing of the eye.

2:45

However, the infectious etiologies may be associated with

2:49

fever and usually have a nidus that is leading

2:54

to the inflammation of the globe.