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Squamous Cell Carcinoma of the Nasolacrimal Sac

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This is a patient who presented with lateral

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deviation of the right globe.

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As we scroll,

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we see a large process, which is in the extraconal space,

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but more importantly, centered at the lacrimal sac region.

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The normal lacrimal sac on the left side is seen at the

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edge of the orbit and junction with the anterior ethmoid.

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So here would be our normal lacrimal sac.

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As you can see,

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we have a process that is quite large, which is

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infiltrating the extraconal space, as well as extending to

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the nasal soft tissues and deviating the globe laterally.

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This is a very large mass centered

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at the nasal lacrimal sac.

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The benign conditions of the nasal lacrimal sac that

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I would consider would be polyps and fibromas.

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However, this is a relatively aggressive looking abnormality.

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And therefore, we would have to consider

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more likely malignancies.

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Malignancies of the nasal lacrimal sac consist

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of squamous cell carcinoma, melanoma,

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lymphoma and transitional cell carcinoma.

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Because of the soft tissue infiltration over the

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eyelid and extension into the subcutaneous fat,

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malignancy is most likely.

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However, the imaging characteristics of these malignancies,

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all are the same.

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And therefore, we cannot predict what the histology is.

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What I would probably do is just go with the most common,

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which is squamous cell carcinoma.

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What we do want to look for is bony erosion of the medial

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orbital wall common with the ethmoid sinus,

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and to determine whether or not the tumor

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has breached the conal space,

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or extended intraconally.

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We cannot tell the distinction between this

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mass and the medial rectus muscle.

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Let's look at this on coronal imaging.

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This is a coronal reconstruction from the axial

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thin-section images, and what it demonstrates is the

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infiltration of the mass to involve the medial rectus muscle,

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as well as the inferior rectus muscle and

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infiltration as well of the superior oblique muscle.

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The intraconal fat, far anteriorly,

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also appears to be involved.

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Despite the fact that this lesion has

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arisen from the nasal lacrimal sac,

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it likely will require complete orbital exenteration

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because of the involvement of the extraocular

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muscles and the intraconal space.

Report

Description

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Tags

Orbit

Neuroradiology

Neuro

Neoplastic

Head and Neck

CT

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