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Training Collections
Library Memberships
On-demand course library with video lectures, expert case reviews, and more
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Practice-focused training programs designed to help you gain experience in a specific subspecialty area.
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Unlock access to our full Course Library and all self-paced Fellowships.
Noon Conference (Free)
Get access to free live lectures, every week, from top radiologists.
Case of the Week (Free)
Get a free weekly case delivered right to your inbox.
Dr. Resnick's MSK Conference
Learn directly from the MSK Master himself.
Lower Extremities MRI Conference
Musculoskeletal Imaging
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For Private Practices
Upskill in high growth, advanced imaging areas.
Emergency Call Prep
Prepare trainees to be on call for the emergency department with this specialized training series.
Lesson
Introduction
1 topic,
Lesson
Meningiomas
15 topics, 59 min.
Case: Assessing Lesion Position
4 m.Intra-Axial vs. Extra-Axial Lesions
3 m.Case: Typical Locations of Meningiomas
3 m.Case: Defining Meningioma
2 m.Case: Meningioma Appearance on MRI
6 m.Case: Meningioma Enhancement
3 m.Case: Meningioma vs. Schwannoma
5 m.Case: Meningiomas in the Posterior Fossa
5 m.Case: Planum Sphenoidale Meningioma with Orbital Apex Extension
4 m.Case: Suprasellar Meningioma
7 m.Case: Optic Nerve Meningioma
6 m.Case: Vascular Encasement of Meningioma With Absent Vasogenic Edema
3 m.Case: Parafalcine Meningioma
6 m.Case: Meningiomatosis
5 m.Case: Solitary Fibrous Tumor
6 m.Lesson
Non-glial Tumors
9 topics, 38 min.
Case: Hemangioblastoma and Von Hippel-Lindau Syndrome
7 m.Case: Recurrent Hemangioblastoma
3 m.Case: Spinal Hemangioblastoma
4 m.Case: VHL Renal Lesions
6 m.Case: Endolymphatic Sac Tumor
3 m.Case: Central Neurocytoma
6 m.Case: Lhermitte-Duclos Disease/Dysplastic Cerebellar Gangliocytoma
6 m.Case: Epidermoid Cyst
4 m.Case: Rhabdomyosarcoma
4 m.Lesson
2021 WHO CNS Tumor Classification
10 topics, 44 min.
Introduction to Glioma Imaging
1 m.Introduction to the 2021 WHO CNS Tumor Classification
5 m.Neuroimaging Techniques For CNS Tumors
13 m.Pediatric Brain Tumors Based on Molecular Genetics: Medulloblastomas
2 m.Pediatric Brain Tumors Based on Molecular Genetics: Ependymomas
6 m.Pediatric Brain Tumors Based on Molecular Genetics: Diffuse Midline Gliomas
4 m.Adult Brain Tumors Based on Molecular Genetics: Solitary Fibrous Tumors and Hemangiopericytoma
2 m.Adult Brain Tumors Based on Molecular Genetics: Circumscribed Gliomas
2 m.Adult Brain Tumors Based on Molecular Genetics: Glioblastomas
3 m.Adult Brain Tumors Based on Molecular Genetics: Diffuse Gliomas
9 m.Lesson
Gliomas
21 topics, 1 hr. 32 min.
IDH-Wildtype Gliomas
8 m.Case: Primary IDH-Wildtype Glioma
3 m.Case: IDH-Wildtype Glioma
6 m.Case: IDH-Wildtype Gliobastoma with Epedymal Extension
7 m.IDH-Mutant Gliomas
9 m.Case: IDH-Mutant Astrocytoma, FLAIR Mismatch, Grade 2
5 m.Case: IDH-Mutant Astrocytoma, Grade 2
3 m.Case: IDH-Mutant Oligodendroglioma, Grade 2
2 m.Case: Oligodendroglioma, Grade 3
3 m.Case: CNS Lymphoma
4 m.H3 and BRAF Gliomas
9 m.Case: H3K27M Midline Glioma, Grade 4
3 m.Case: H3K27 Glioma
3 m.Case: BRAF V600E Tumor
5 m.T2 FLAIR Mismatch Sign of IDH-Mutant Astrocytomas
8 m.Case: T2 FLAIR Mismatch Sign, Astrocytoma – 31 y/o Female
2 m.Case: T2 FLAIR Mismatch Sign, Astrocytoma – 28 y/o Male
1 m.Case: IDH Mutant Astrocytoma, No Mismatch Sign
2 m.Approach to Intra-Axial Tumors: Tumor Mimics, Non-Neoplastic Lesions
12 m.Final Pearls, Pediatric Non-Gliomas
5 m.Summary
2 m.0:01
This is an example of a 41-year-old male patient
0:04
presenting with headaches and seizures,
0:07
and has a relatively well-defined
0:10
T2 hyperintense lesion
0:12
in the right frontal operculum.
0:15
As you can see,
0:16
it does not show any contrast enhancement.
0:18
And here's the tumor seen
0:20
on the sagittal weighted images,
0:21
sagittal post-contrast images.
0:23
You can see the tumor is in the frontal,
0:27
infralateral frontal lobe,
0:28
in the precentral region and frontal operculum .
0:32
And this tumor is not showing you dark signal on
0:36
the FLAIR images in the central part of the tumor,
0:39
as we expect for a T2 FLAIR mismatch sign to be.
0:42
In fact, it's bright,
0:44
homogeneously bright on the FLAIR images.
0:47
And that is the reason I would not call
0:49
this a T2 FLAIR mismatch sign.
0:51
But that does not mean that this cannot
0:54
be an IDH mutated astrocytoma.
0:56
If I see the sign, that's 100% positive predictive
0:59
value to call this an IDH mutated astrocytoma.
1:03
If I don't see the sign,
1:05
this could be an IDH mutated astrocytoma,
1:08
or it could be an oligodendroglioma,
1:10
or even it could be an IDH wild-type tumor.
1:12
But because it's a younger patient
1:15
and presenting with this very superficial mass,
1:19
this in fact turned out to be
1:22
an IDH mutated astrocytoma.
1:24
But I would not call this T2 FLAIR mismatch sign
1:26
based on the imaging alone.
Case: IDH Mutant Astrocytoma, No Mismatch Sign
HIDEInteractive Transcript
0:01
This is an example of a 41-year-old male patient
0:04
presenting with headaches and seizures,
0:07
and has a relatively well-defined
0:10
T2 hyperintense lesion
0:12
in the right frontal operculum.
0:15
As you can see,
0:16
it does not show any contrast enhancement.
0:18
And here's the tumor seen
0:20
on the sagittal weighted images,
0:21
sagittal post-contrast images.
0:23
You can see the tumor is in the frontal,
0:27
infralateral frontal lobe,
0:28
in the precentral region and frontal operculum .
0:32
And this tumor is not showing you dark signal on
0:36
the FLAIR images in the central part of the tumor,
0:39
as we expect for a T2 FLAIR mismatch sign to be.
0:42
In fact, it's bright,
0:44
homogeneously bright on the FLAIR images.
0:47
And that is the reason I would not call
0:49
this a T2 FLAIR mismatch sign.
0:51
But that does not mean that this cannot
0:54
be an IDH mutated astrocytoma.
0:56
If I see the sign, that's 100% positive predictive
0:59
value to call this an IDH mutated astrocytoma.
1:03
If I don't see the sign,
1:05
this could be an IDH mutated astrocytoma,
1:08
or it could be an oligodendroglioma,
1:10
or even it could be an IDH wild-type tumor.
1:12
But because it's a younger patient
1:15
and presenting with this very superficial mass,
1:19
this in fact turned out to be
1:22
an IDH mutated astrocytoma.
1:24
But I would not call this T2 FLAIR mismatch sign
1:26
based on the imaging alone.
Report
Faculty
Rajan Jain, MD
Professor of Radiology and Neurosurgery
New York University Grossman School of Medicine
Tags
Oncologic Imaging
Neuroradiology
Neoplastic
MRI
Brain
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