Training Collections
Library Memberships
On-demand course library with video lectures, expert case reviews, and more
Fellowship Certificate™ Programs
Practice-focused training programs designed to help you gain experience in a specific subspecialty area.
Ultimate Learning Pass
Unlock access to our full Course Library and all self-paced Fellowships.
Noon Conference (Free)
Get access to free live lectures, every week, from top radiologists.
Case of the Week (Free)
Get a free weekly case delivered right to your inbox.
Dr. Resnick's MSK Conference
Learn directly from the MSK Master himself.
Lower Extremities MRI Conference
Musculoskeletal Imaging
Emergency Imaging
PET Imaging
Pediatric Imaging
For Training Programs
Supplement your training program with case-based learning for residents, registrars, fellows, and more.
For Private Practices
Upskill in high growth, advanced imaging areas.
Emergency Call Prep
Prepare trainees to be on call for the emergency department with this specialized training series.
Training Collections
Library Memberships
On-demand course library with video lectures, expert case reviews, and more
Fellowship Certificate™ Programs
Practice-focused training programs designed to help you gain experience in a specific subspecialty area.
Ultimate Learning Pass
Unlock access to our full Course Library and all self-paced Fellowships.
Noon Conference (Free)
Get access to free live lectures, every week, from top radiologists.
Case of the Week (Free)
Get a free weekly case delivered right to your inbox.
Dr. Resnick's MSK Conference
Learn directly from the MSK Master himself.
Lower Extremities MRI Conference
Musculoskeletal Imaging
Emergency Imaging
PET Imaging
Pediatric Imaging
For Training Programs
Supplement your training program with case-based learning for residents, registrars, fellows, and more.
For Private Practices
Upskill in high growth, advanced imaging areas.
Emergency Call Prep
Prepare trainees to be on call for the emergency department with this specialized training series.
Lesson
Introduction
1 topic,
Lesson
Meningiomas
15 topics, 59 min.
Case: Assessing Lesion Position
4 m.Intra-Axial vs. Extra-Axial Lesions
3 m.Case: Typical Locations of Meningiomas
3 m.Case: Defining Meningioma
2 m.Case: Meningioma Appearance on MRI
6 m.Case: Meningioma Enhancement
3 m.Case: Meningioma vs. Schwannoma
5 m.Case: Meningiomas in the Posterior Fossa
5 m.Case: Planum Sphenoidale Meningioma with Orbital Apex Extension
4 m.Case: Suprasellar Meningioma
7 m.Case: Optic Nerve Meningioma
6 m.Case: Vascular Encasement of Meningioma With Absent Vasogenic Edema
3 m.Case: Parafalcine Meningioma
6 m.Case: Meningiomatosis
5 m.Case: Solitary Fibrous Tumor
6 m.Lesson
Non-glial Tumors
9 topics, 38 min.
Case: Hemangioblastoma and Von Hippel-Lindau Syndrome
7 m.Case: Recurrent Hemangioblastoma
3 m.Case: Spinal Hemangioblastoma
4 m.Case: VHL Renal Lesions
6 m.Case: Endolymphatic Sac Tumor
3 m.Case: Central Neurocytoma
6 m.Case: Lhermitte-Duclos Disease/Dysplastic Cerebellar Gangliocytoma
6 m.Case: Epidermoid Cyst
4 m.Case: Rhabdomyosarcoma
4 m.Lesson
2021 WHO CNS Tumor Classification
10 topics, 44 min.
Introduction to Glioma Imaging
1 m.Introduction to the 2021 WHO CNS Tumor Classification
5 m.Neuroimaging Techniques For CNS Tumors
13 m.Pediatric Brain Tumors Based on Molecular Genetics: Medulloblastomas
2 m.Pediatric Brain Tumors Based on Molecular Genetics: Ependymomas
6 m.Pediatric Brain Tumors Based on Molecular Genetics: Diffuse Midline Gliomas
4 m.Adult Brain Tumors Based on Molecular Genetics: Solitary Fibrous Tumors and Hemangiopericytoma
2 m.Adult Brain Tumors Based on Molecular Genetics: Circumscribed Gliomas
2 m.Adult Brain Tumors Based on Molecular Genetics: Glioblastomas
3 m.Adult Brain Tumors Based on Molecular Genetics: Diffuse Gliomas
9 m.Lesson
Gliomas
21 topics, 1 hr. 32 min.
IDH-Wildtype Gliomas
8 m.Case: Primary IDH-Wildtype Glioma
3 m.Case: IDH-Wildtype Glioma
6 m.Case: IDH-Wildtype Gliobastoma with Epedymal Extension
7 m.IDH-Mutant Gliomas
9 m.Case: IDH-Mutant Astrocytoma, FLAIR Mismatch, Grade 2
5 m.Case: IDH-Mutant Astrocytoma, Grade 2
3 m.Case: IDH-Mutant Oligodendroglioma, Grade 2
2 m.Case: Oligodendroglioma, Grade 3
3 m.Case: CNS Lymphoma
4 m.H3 and BRAF Gliomas
9 m.Case: H3K27M Midline Glioma, Grade 4
3 m.Case: H3K27 Glioma
3 m.Case: BRAF V600E Tumor
5 m.T2 FLAIR Mismatch Sign of IDH-Mutant Astrocytomas
8 m.Case: T2 FLAIR Mismatch Sign, Astrocytoma – 31 y/o Female
2 m.Case: T2 FLAIR Mismatch Sign, Astrocytoma – 28 y/o Male
1 m.Case: IDH Mutant Astrocytoma, No Mismatch Sign
2 m.Approach to Intra-Axial Tumors: Tumor Mimics, Non-Neoplastic Lesions
12 m.Final Pearls, Pediatric Non-Gliomas
5 m.Summary
2 m.0:00
So here is a 31-year-old female
0:02
presenting with headaches.
0:04
And the MRI shows a rather well-defined
0:09
mass in the right medial temporal lobe.
0:12
And you can see that the tumor is
0:15
kind of homogeneously bright,
0:17
very well-defined on T2 two weighted images.
0:20
But more importantly is majority of the tumor is
0:24
dark in the central part on the FLAIR images,
0:27
except this thin peripheral bright
0:29
rim on the FLAIR images.
0:31
And this is what we call a T2 FLAIR mismatch sign.
0:35
And typically, these tumors also do not
0:39
show any enhancement.
0:39
As you can see,
0:40
there is no enhancement
0:42
on the post-contrast images.
0:43
And majority of these tumors also show very
0:47
facilitated diffusion in this
0:49
central portion of the tumor,
0:51
which is almost gelatinous
0:54
and very soft on surgery.
0:57
Neurosurgeons will classically
0:59
tell you that these are
1:00
gelatinous soft tumors,
1:01
which are very easy to resect.
1:03
And this is what we have described
1:07
as the T2 FLAIR mismatch sign.
1:09
A classic example in a younger patient.
1:12
And once we see this sign,
1:13
we know that this tumor is going to be IDH-mutated
1:17
non-codeleted astrocytoma.
1:20
And this is one example over here.
Case: T2 FLAIR Mismatch Sign, Astrocytoma – 31 y/o Female
HIDEInteractive Transcript
0:00
So here is a 31-year-old female
0:02
presenting with headaches.
0:04
And the MRI shows a rather well-defined
0:09
mass in the right medial temporal lobe.
0:12
And you can see that the tumor is
0:15
kind of homogeneously bright,
0:17
very well-defined on T2 two weighted images.
0:20
But more importantly is majority of the tumor is
0:24
dark in the central part on the FLAIR images,
0:27
except this thin peripheral bright
0:29
rim on the FLAIR images.
0:31
And this is what we call a T2 FLAIR mismatch sign.
0:35
And typically, these tumors also do not
0:39
show any enhancement.
0:39
As you can see,
0:40
there is no enhancement
0:42
on the post-contrast images.
0:43
And majority of these tumors also show very
0:47
facilitated diffusion in this
0:49
central portion of the tumor,
0:51
which is almost gelatinous
0:54
and very soft on surgery.
0:57
Neurosurgeons will classically
0:59
tell you that these are
1:00
gelatinous soft tumors,
1:01
which are very easy to resect.
1:03
And this is what we have described
1:07
as the T2 FLAIR mismatch sign.
1:09
A classic example in a younger patient.
1:12
And once we see this sign,
1:13
we know that this tumor is going to be IDH-mutated
1:17
non-codeleted astrocytoma.
1:20
And this is one example over here.
Report
Faculty
Rajan Jain, MD
Professor of Radiology and Neurosurgery
New York University Grossman School of Medicine
Tags
Oncologic Imaging
Neuroradiology
Neoplastic
MRI
Brain
© 2024 Medality. All Rights Reserved.