Upcoming Events
Log In
Pricing
Free Trial

Case: Meningioma vs. Schwannoma

HIDE
PrevNext

0:00

Dr. Laser, this is a 28

0:02

year-old man. He's got a known brain tumor.

0:04

He's had an operation.

0:05

There's some packing in the left

0:07

oto mastoid air cell region.

0:09

Let's do a little bit of scrolling

0:11

on the left. We have an extraxial mass flare

0:14

in the center, we have an axial T2,

0:17

there's the mass,

0:18

there's the compression of the brain stem

0:21

and the mass appears riding along the dural edge

0:25

portions of the tentorium cerebelli involved.

0:28

There's the cochlea.

0:30

It's a little hard to see the 7th and

0:31

8th nerve complexes,

0:32

but a big differential here is

0:34

is this a cerebellopontine angle meningioma?

0:38

Or is it a vestibular schwannoma?

0:41

Now in my experience, uh,

0:43

many schwannomas in this area are cystic.

0:45

In fact, they can even look like epidermoids,

0:48

and while you can get cystic meningiomas,

0:50

this is really uncommon.

0:52

Uh, you'll also see

0:53

little microcystic meningiomas like you have here,

0:56

but uh, dominant cysts or the whole thing being

0:58

cystic with some nodular enhancement

1:00

much more typical of a schwannoma,

1:02

and that's true. By the way, in MRI,

1:04

schwannomas tend to be pretty cystic

1:05

in the peripheral aspect of the body.

1:08

This patient has a dural tail

1:11

and what's the other name for that dural tail sign?

1:20

Dovetail sign

1:21

be another name for

1:22

dovetail sign or dovetail enhancement,

1:24

and how often have you seen that? With a schwannoma

1:26

very rarely, very rarely, maybe a plexiform one

1:29

it could happen,

1:29

but I can't remember the last time I saw it.

1:35

you know, is there a hyperostotic reaction

1:37

and that can be a little challenging on an MRI,

1:40

but I will say this

1:41

everything is just a little bit thicker and blacker

1:44

on the left side than it is on the right side

1:47

so you should be,

1:47

you know, perhaps a little bit suspicious

1:50

that there are some bone changes

1:52

and these bone changes can be

1:54

osteolytic, but they're more commonly sclerotic.

1:57

The fact let's bring down an SWI

1:59

or susceptibility-weighted image

2:01

to see if there's a little more

2:03

prominent hypointensity in the bone area

2:06

and admittedly that's hard to tell.

2:08

Perhaps right here maybe there's a little hyperostosis,

2:11

but within the lesion, there's a lot of low signal,

2:14

and while those signals could represent hemosiderin and blood

2:17

uh, in this case, calcification,

2:19

especially this sort of chunky shape or irregular shape

2:21

seems most likely, so calcification

2:24

it occurs in Schwannoma, but

2:27

between Schwannoma and Meningioma,

2:29

what do you like better for calcifications,

2:30

Meningioma? It's pretty rare in a Schwannoma.

2:32

Yeah, it is it is rare. In fact,

2:35

typically none.

2:37

Meningioma is what about 20%

2:40

yeah, that's about right

2:42

and um as far as the enhancement goes,

2:44

let's bring back down our

2:46

axial C plus. Image

2:48

tell me a little bit

2:49

about the internal character of the enhancement

2:51

and Meningioma versus Schwannoma is that helpful at all.

2:55

Uh, it can be,

2:56

uh and the Meningioma typically has uniform enhancement.

3:00

The Schwannoma can have heterogeneous enhancement, um

3:03

about 10% of the time, but it's uh,

3:06

Meningiomas will avidly enhance quickly

3:09

and uh or are light bulb bright

3:11

so more intense,

3:13

frequently more homogeneous

3:15

more early.

3:16

Uh, this one's enhancing a little more heterogeneously,

3:19

but it does have that nice

3:20

little dural tail or dovetail sign

3:22

which helps you a lot.

3:23

Now another aspect of this lesion that

3:25

helps you favor Meningioma is it's growing

3:28

along the surface of the cerebellum,

3:30

but not into the IAC.

3:32

It's not growing directly

3:33

into the internal auditory canal,

3:34

it's behind it.

3:36

and typically

3:37

Schwannomas will

3:37

arise from and involve the internal auditory canal

3:41

or porus acousticus.

3:42

This lesion does not.

3:43

We didn't do spectroscopy in this case,

3:45

but Meningiomas have an elevated alanine

3:48

on SPECT and Schwannomas have elevated tyrosine and GABA,

3:53

and then finally, if you've got a CT,

3:54

Schwannomas are not typically hyperdense,

3:58

um and Meningiomas are often hyperdense.

4:01

Do you have any other comments on this one?

4:02

We do have an ADC map, which shows that it

4:03

doesn't diffusion restrict very much,

4:04

even though this is a hard firm lesion.

4:06

There's no real dark areas right here on the ADC map

4:11

as you would expect

4:13

for something that restricts diffusion.

4:15

Other comments before we move off this case.

4:17

Only

4:17

other comment I would mention is the Mass Effect.

4:19

This would be a call to the clinician

4:22

just due to the mass effect upon the brainstem,

4:24

so I think that would probably be the most important

4:26

clinical aspect of this case.

4:28

Yeah, although the mass effect has probably

4:29

been there for some time,

4:30

it's chronic correct.

4:31

It's very important although the patient is in no

4:34

imminent danger.

4:35

And I will say mass effect in distinguishing

4:37

between Meningioma and Schwannoma.

4:39

Not so helpful because

4:40

they both can produce a fair amount of mass effect.

4:42

So that concludes our comparison

4:44

in the posterior fossa of Meningioma versus Schwannoma.

Report

Faculty

Stephen J Pomeranz, MD

Chief Medical Officer, ProScan Imaging. Founder, MRI Online

ProScan Imaging

Tags

Oncologic Imaging

Neuroradiology

Neoplastic

MRI

Brain

© 2024 Medality. All Rights Reserved.

Contact UsTerms of UsePrivacy Policy