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Case number 9.

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The next case is a 55-year-old male with word retrieval difficulty.

0:07

On the MRI here, we see asymmetric left perisylvian atrophy.

0:13

So it's the axial image. Here's the coronal image.

0:15

You can see the definite asymmetry and the size of the sulci here.

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So this patient has Logopenic Progressive Aphasia.

0:25

When we were talking about FTD, we had talked about the nonfluent

0:28

and the semantic, a variants of primary progressive aphasia.

0:31

But this is really something different.

0:33

The logopenic primary progressive aphasia, again, presents with word retrieval

0:38

difficulties, which is what this patient had, and sentenced repetition problems.

0:42

We see the atrophy of the temporoparietal junction.

0:45

And this is really a subcategory of Alzheimer's disease, unlike these two,

0:50

which are really a subcategory of frontal temporal dementia.