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Challenging Body Case 1

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This is my PACS and we have a list of cases.

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There's about nine cases over here. This is all de identified.

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These are random medical record numbers, random accession numbers, random

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date of births, all assigned to January 1st. So we don't need to

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worry about any of that stuff. And over the next hour,

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we're just going to go through these nine cases. There'll be a multiple

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choice question or two after each case. The plan is to just scroll

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through them. I'm not going to say much as I scroll through it.

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At least I'm gonna try not to say much, just so you guys

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can go through your own search pattern. We'll ask a question and then

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we'll talk a little bit about the case right after it.

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Most of these, as you can see, are MRI cases. There's a few

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CT cases. The point here is to show you some

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cases which I think are challenging, are kind of fun

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to go through. So let's start with our first case. This is gonna

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be here. It's gonna be a CT case to warm everybody up.

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Now let's do a two by two. Let's take some of the annotations away. I

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should do a one by one here. And I'm just gonna start scrolling

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through it, the axial images. And first time around, maybe just

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have a look, gather some thoughts about some of the findings that you're

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seeing. If I'm scrolling too fast or too slow,

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feel free to chime in in the chat box. So these are the

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axial images. You can see it's a contrast enhanced CT scan.

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A lot of stuff going on as we scroll through these axial images.

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I'm gonna scroll back up one more time so you guys can have

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a look and just see everything now that you've had

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just a few seconds to absorb some of the findings that

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are here. And I'll move on to the coronals as well.

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So you get another chance to look at everything.

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And so you're seeing the same findings in a different plane.

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And clearly, there's sort of a diffuse process going on. It may also

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be important to look at some of the organs just to kind of

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help you figure out what could be causing that diffuse process.

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These are the sagittal images. And I'll just sort of

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put it on bone windows as well. So you get to see the

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bones at least in one of the planes. All right, you just see

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there's something in the chat box over here.

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Everyone's had a chance to look at the cases. If we could have

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the first multiple choice question up for the audience, please.

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So we're gonna ask what the most likely diagnosis here is.

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Or options. TB, Pseudomyxoma, Encapsulating peritoneal sclerosis. It's a

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mouthful there. And Barium peritonitis as well. So clearly, something is

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involving the peritoneum. What is the right answer over here? All right,

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so we are neck and neck with tuberculous peritonitis and encapsulating peritoneal

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sclerosis. So that's great. So let's go through

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some of the answers here. And I think somebody chimed in in the

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chat box and also said encapsulating peritoneal sclerosis. All right, so

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here we have a CT scan. The history is probably abdominal pain.

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I don't want to harp too much on history, unless it's really relevant

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to making the diagnosis. I'm not sure if it is in this instance.

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And as you look at it, it's a contrast enhanced CT scan.

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You're seeing this Hyperattenuating curvilinear content that's sort of lining

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the peritoneum lining. And now I can window it a little bit better.

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Maybe you can see it now. Surrounding the spleen, surrounding the right

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subhepatic space over here in the liver, the left subhepatic space,

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going through all the respective ligaments. As you go down, you can see

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it beautifully sort of outlining some of the paracolic gutters. You can

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see it beautifully outlining multiple loops of small bowel where the mesentery

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is, going all the ways down to the pelvis. And so this is

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really a diffuse process. And so all. This is a diffuse process involved

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in the peritoneum. So how can we sort of narrow it down to

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one of the four options that we've given?

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So I think Pseudomyxoma peritonei was one of the things I think nobody

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answered or maybe very few answered. And I think we can sort of

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exclude that because those are often seen with mucinous appearing, secreting

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neoplasms. You can't get these calcifications, but classically, they'll

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get scalloping on the borders of the liver and spleen. And so,

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yes, there is some free fluid in the cites here. You're not getting

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that scalloping and mass effect upon those organs. And so we can probably

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put that lower on our differential diagnosis. I think TB, you know, I

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put it there because whenever you see calcifications anywhere in the abdomen

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and pelvis, you have to think of TB, particularly when it's diffused like

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this. So, you know, that's one possibility, and certainly tuberculosis can

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affect the peritoneum. But, you know, the best answer in this instance,

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given all the other findings that I'll go through, is probably encapsulating

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peritoneal sclerosis. And so one of the things you have to look at

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is what else is going on in this case? The liver and spleen

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look okay. Look at the kidneys. They're small, right? They're shrunken kidneys

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with numerous cysts. And so when you see that appearance of small kidneys

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with numerous cysts, you gotta think of Acquired Cystic disease of dialysis.

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That's one of the things you have to think about. So when you

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look at that, you say, okay, when I see that appearance on the

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kidneys, it's a good chance the patient's on dialysis or has been on

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dialysis, peritoneal dialysis. And so whenever I think about that, I say,

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okay, well, what are the complications associated with peritoneal dialysis

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that I can see in the abdomen and pelvis? And one of them

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is encapsulating peritoneal sclerosis. It's a relatively uncommon complication,

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but it's really characterized by areas of intraperitoneal inflammation and

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fibrosis. And really when you get to the end stage, you gonna to see

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these very thick and coarse calcifications. At an earlier stage, you'll

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just see thickening of the peritoneum lining without these calcifications

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surrounding the peritoneum. But it can be quite devastating. As you can

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see what it's doing here to a lot of these loops of small

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bowels, it's sort of just not allowing them to breathe, right? These small

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loops of bowel are clustered in one location. It's often called cocooning

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of the small bowel. And oftentimes, you know, the calcifications themselves

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are not going to cause issues, but what they do to the other

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organs, particularly the small bowel, can lead to a high rate of morbidity

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and mortality. And so the other finding that I wanted to show you

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that supports the diagnosis patient is in renal failure, has been a renal

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failure, is this beautiful example of Rugger Jersey spine. I have to say,

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you know, you read about it in the textbooks,

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but this is one example where you really do see it very nicely.

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And so, you know, the combination of the kidney appearance, the Rugger Jersey

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spine tells this patient, you know, has renal failure, has been on dialysis,

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and then you see these findings. I think of the four options,

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encapsulating peritoneal sclerosis is probably the best option over there.

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So that's the first case.

Report

Description

Faculty

Mahan Mathur, MD

Associate Professor, Division of Body Imaging; Vice Chair of Education, Dept of Radiology and Biomedical Imaging

Yale School of Medicine

Tags

Peritoneum/Mesentery

Gastrointestinal (GI)

CT

Body

Acquired/Developmental

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