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Okay, now that we've seen a lot of cases of

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Crohn's disease, we want to talk a little bit

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about some other things that we need to look for

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in patients with Crohn's or ulcerative colitis.

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And higher on that list is the fact that they

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do often have extraintestinal manifestations,

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as we've all learned in our medical school.

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Crohn's sees this, especially colonic Crohn's

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disease, as well as UC, which is a little

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more notorious for having these findings.

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So you can find findings in

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multiple different organ systems.

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MSK, you can have the seronegative

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spondyloarthropathy, where you get changes in

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the spine and the SI joints with inflammation.

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In the biliary tree, you can get changes that

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look like PSC, and ultimately, that can also

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convert all the way to cholangiocarcinoma.

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You can also get things like cholelithiasis,

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and another thing to always keep an eye out for is in cases

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with severe inflammation, portal venous thrombosis

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is a complication that you don't want to be missing.

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The skin isn't really our region, but it's important

1:00

to remember that they do have skin changes such as

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erythema nodosum, pyoderma gangrenosum, and then they

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have ocular changes such as episcleritis and scleritis.