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Extramedullary Hematopoiesis of the Epidural Space

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I'd like to show a few cases of disease in the epidural

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space which is unassociated with the vertebral bodies and

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yet still is likely to cause compression of the spinal cord.

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And I'm going to show a series of cases here.

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This is a patient who has these low signal intensity areas

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in the epidural fat, compressing the spinal cord anteriorly.

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We notice that these low signal intensity areas on

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T2-weighted scanning are the same signal intensity

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as the bone marrow. This is an additional case.

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This patient has had a post myelogram CT performed, and we see

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that there is soft tissue in the posterior epidural space,

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which is compressing the thecal sac anteriorly.

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We notice that the bones don't look particularly good here,

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this sort of osteopenic anemic-looking bones.

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And even in the lumbar region,

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we do have areas of abnormal signal intensity in the

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anterior epidural space associated with the sacrum.

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Both of these cases were patients who had

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extramedullary hematopoiesis, that is,

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red marrow cells effectively in the epidural space,

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which can lead to compression of the spinal cord.

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We see that this is epidural on the axial CT

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scan, post myelogram, the cord, the thecal sac,

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and then in the epidural space, the soft tissue.

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Here is another case of extramedullary hematopoiesis.

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In this case, we see that there is high signal intensity

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on post-contrast imaging in the soft tissue on either side of

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the spinal cord in the epidural space,

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and that also is typical of active marrow in the epidural space.

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And this has led to compression of the thecal sac in a

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polygonal pattern that has been described as

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a sign of extramedullary hematopoiesis.

Report

Description

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Tags

Spine

Neuroradiology

Musculoskeletal (MSK)

Metabolic

MRI

CT

Acquired/Developmental

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