Interactive Transcript
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So, neuroendocrine tumors can be
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functional or non-functional.
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Once they are functional, they are detected
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earlier because of their hormone secretions.
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And if they are non-functional, they are detected
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later because they grow before presenting
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with abdominal pain or other symptoms due
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to the mass effect on the overlying organs.
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Non-functional NETs (Neuroendocrine Tumors) are usually large and necrotic
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when detected and can sometimes mimic SPN (Solid pseudopapillary neoplasm).
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But again, gender and
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location are more important.
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In making a diagnosis, usually, necrosis is mostly
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central and they do not have hemorrhagic content.
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Hemorrhage is more common with SPN.
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Fifty percent of non-functional tumors, once they
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grow and become more than 5 cm in size, have
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the potential to be possibly malignant
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and undergo metastasis when detected.
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And once they are cystic, they
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undergo degeneration and growth, but
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the evident enhancement during the
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arterial phase will still be there.
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In the retained parenchyma, so you can
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differentiate based on those characteristics on
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imaging, but again there are other ways like doing
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tumor markers or urine HIA or chromogranin to
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differentiate whether it is NET or SPN.
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