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Complex Regional Pain Syndrome

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This is a child who had an injury more proximally in her arm,

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which resolved, but she continued to have pain

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more distally.

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And this is the X-ray on the left,

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and an MRI on the right.

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The MRI is a fat-suppressed fluid-sensitive sequence,

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meaning that anything that's fat is going to be dark,

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anything that's edema or fluid, it's going to be bright.

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What's striking on the plain radiograph is the amount of osteopenia that's present.

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How do you judge osteopenia?

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Well, look at the trabecular pattern.

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It's striking, right?

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You can almost count every individual trabecula.

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And look how it gets more dark

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or loosened as you go from the central metaphysis to the periphery

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involving the metaphysis, from the diaphysis to the metaphysis.

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And it's centered around joints.

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Here's the PIP joint, DIP joint, sort of extensive.

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So this is called periarticular osteopenia,

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meaning that the degree of osteopenia is

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accentuated more so around joints.

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So there's periarticular osteopenia here, here, here.

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Basically, everywhere that you see it.

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Another objective way of determining

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whether it's osteopenia or not, is looking at the thickness of the cortex.

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For example, you should be able to see the cortex on either side of

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this proximal phalanx well-defined.

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But here, I don't know where the cortex ends and the medullary cavity begins.

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Final way, if you are able to

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determine the cortex thickness,

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for example, let's say we could see the cortical thickness

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was from here to here.

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Let's say that was the cortical thickness.

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If you double this value, it would be something that went out to here.

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That value should be at least half

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the length or half the width of your medullary cavity.

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And it's not clearly half that, is it?

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Right.

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So we know objectively, and even subjectively,

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you have osteopenia.

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Osteopenia is one of the hallmarks of this

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condition, which is chronic regional pain syndrome.

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It typically happens after some traumatic event

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more proximately. On the MRI,

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what are you going to see?

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You're going to see these patchy areas

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of STIR signal hyperintensity, likely indicating edema.

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Centered around the metaphysis,

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you can see it over here, over here.

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These are very well looked.

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This is not artifact, this is actually

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abnormal signal within the marrow.

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And oftentimes, the physis will get

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a little wider, it'll get more accentuated, as you see over here.

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But what you're really looking for is these,

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are these areas of STIR bright signal in the marrow.

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Sometimes, you can actually even have

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atrophy of the skin, atrophy of the soft tissues,

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so on and so forth, which is I think more difficult to appreciate on MRI.

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So this is a great example of chronic regional pain syndrome.

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A very important thing to look for

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when you can't find a reason for pain.

Report

Faculty

Mahesh Thapa, MD, MEd, FAAP

Division Chief of Musculoskeletal Imaging, and Director of Diagnostic Imaging Professor

Seattle Children's & University of Washington

Tags

X-Ray (Plain Films)

Syndromes

Pediatrics

Non-infectious Inflammatory

Musculoskeletal (MSK)

MRI

Idiopathic

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