Morton’s Neuroma

  • Morton neuroma is a nonneoplastic thickening of the soft tissues around the digital nerve as it passes the intermetatarsal ligament of the metatarsal heads
  • Most often occurs between the third and fourth toes
  • May occur as a result of entrapment in the area of the transverse intermetatarsal ligament, or as the result of compression/repetitive microtrauma
  • Typical symptom is sharp burning forefoot pain in the characteristic location
  • MRI shows an interdigital mass at the plantar aspect between the involved metatarsal heads
  • The mass is low or intermediate signal on T1 and T2, often with intense contrast enhancement
  • Morton’s neuroma is nine times more common in females than males
  • Fibroid in a prior surgical bed is nearly indistinguishable from a neuroma
  • 10% of cases are bilateral
  1. Xu Z, Duan X, Yu X, Wang H, Dong X, Xiang Z. The accuracy of ultrasonography and magnetic resonance imaging for the diagnosis of Morton’s neuroma: a systematic review. Clin Radiol 2015: 70(4):351-358
  2. Zanetti M, Weishaupt D. MR imaging of the forefoot: Morton neuroma and differential diagnoses. Semin Musculoskel Radiol 2005; 9(3):175-186

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