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Nipple Discharge Overview

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Our next symptom is nipple discharge.

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And again, there's an ACR appropriateness

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criteria for evaluation of nipple discharge.

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So I advise you to check that out

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in JACR and on the ACR website.

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Nipple discharge can be physiological.

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Usually, when it's physiological, it's bilateral

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and coming from multiple duct orifices.

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It can be white, yellow, or green.

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Pathological nipple discharge is usually clear

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or bloody and, um, generally unilateral coming

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from a single duct opening and spontaneous.

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The ACR recommends that for physiological

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nipple discharge, um, the referring

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provider should do a clinical evaluation,

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but really no imaging is indicated.

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For pathological nipple discharge,

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that's the clear or bloody unilateral discharge.

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If the patient's under age 30,

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ultrasound is recommended first with mammography

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at the radiologist's discretion.

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Again, we have that intermediate age,

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age 30 to 39, where ultrasound and mammogram,

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as the first test, both get equal.

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Ratings and then age 40 and up.

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It's recommended to start with a

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mammogram and then perform an ultrasound.

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Our protocol for under age 30, we'll do the

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ultrasound first and then age 30 and up.

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We'll start with the mammogram

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and then go to ultrasound.

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So it's just that age 30 to 39

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where we've decided for our group.

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It makes more sense to start with the mammogram.

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And then go to ultrasound.

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Uh, we'll do full bilateral CC and MLO

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views, and we perform retroareolar spot

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magnification views with the nipple in

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profile in both the CC and lateral projection.

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Sometimes that helps us with, um,

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masses right behind the nipple and

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calcifications behind the nipple.

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And then we do an ultrasound of the retroareolar

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and periareolar breast, paying specific

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attention to the, um, subareolar ducts.

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And, um, trying to figure out if

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there's a mass inside the duct that

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may be causing the patient's discharge.

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There are a few different causes of discharge.

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I mean, obviously, it occurs

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physiologically, but then for these, um,

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pathological, uh, nipple discharge, it can

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be related to intraductal papillomas.

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That's a very frequent cause.

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Sometimes just duct ectasia

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or wide ducts can cause it.

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And then malignancy, um, um, is

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reported in 5 to 21 percent of cases.

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So that's a pretty wide range.

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But we know that the risk of

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malignancy increases with age.

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So it's really only about 3 percent at age 40,

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but 32 percent if the patient's over age 60.

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So we want to be careful about this,

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especially in our older patient population.

Report

Faculty

Lisa Ann Mullen, MD

Assistant Professor; Breast Imaging Fellowship Director

Johns Hopkins Medicine

Tags

Women's Health

Ultrasound

Non-infectious Inflammatory

Neoplastic

Mammography

Idiopathic

Breast

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