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43-year-old woman with diffuse left breast pain and palpable lump. Family history of breast cancer

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Our next patient is a 43-year-old

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woman with diffuse left breast pain and

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palpable lump with a family history of

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breast cancer in her mother at age 37.

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So for this patient, we performed

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a bilateral diagnostic mammogram.

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You have CC views back-to-back on the top

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of the screen and MLO views on the bottom.

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And you can see pretty clearly that

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there's a lot of asymmetric density in

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the left breast, maybe a little bit of

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skin thickening compared to the right.

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There's some large lymph nodes, certainly

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this one in the lower left axilla

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is large, and lots of density there.

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So we'll take a closer look.

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Here's the CC view and then tomosynthesis

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images through that CC view.

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It looks like there may be

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some masses here centrally.

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There's the nipple.

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Pull up the MLO view.

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You can see that asymmetric density,

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some skin thickening here, and a large lymph node.

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Here's the tomosynthesis image showing maybe

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some central masses and that large lymph node

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and certainly thick skin at the lower breast.

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So we went ahead and did ultrasound next.

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Skin is thick, there's some edema,

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kind of hypervascular, there's an

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area that looks more like a mass.

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So in this patient, it was a little bit

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unclear from her presentation whether she

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had diffuse mastitis or she had inflammatory

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breast cancer, and sometimes it can

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be a little bit unclear at the outset.

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There was a strong family history

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of breast cancer in this patient.

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Um, she had some other medical problems,

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but she was considered a high-risk person.

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So we didn't want to just,

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you know, say that this was mastitis.

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So our suggestion was a course of

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antibiotics, and that if she didn't improve

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on antibiotics, then we would perform

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a biopsy or some type of intervention.

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During the course of antibiotics,

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she became much more ill with fever and

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chills and ended up being admitted to

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the hospital for intravenous antibiotics.

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So this is a presumed case of diffuse

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mastitis, and, you know, we will follow up.

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Um, this is actually an active case and we'll

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follow up, and hopefully everything will resolve.

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But even if we are suspecting mastitis, but it's

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questionable, we would want to do a course of

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antibiotics and then follow up afterward,

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and just make sure that everything has resolved.

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If it hasn't, then we would

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certainly do a biopsy.

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We don't want to miss a case

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of inflammatory breast cancer.

Report

Faculty

Lisa Ann Mullen, MD

Assistant Professor; Breast Imaging Fellowship Director

Johns Hopkins Medicine

Tags

Women's Health

Ultrasound

Tomosynthesis

Non-infectious Inflammatory

Mammography

Breast

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